Evidence map›Paper›PMID 42780719›Full record

ArticleActa Cardiologica Sinica2026

Temporal Changes in Nonlinear Heart Rate Variability Following Pulmonary Vein Isolation for Paroxysmal Atrial Fibrillation.

Ting-Wei Ernie Liao, Li-Wei Lo, Yenn-Jiang Lin, Shih-Lin Chang, Yu-Feng Hu, Fa-Po Chung, Tze-Fan Chao, Jo-Nan Liao, Hui-Wen Yang, Men-Tzung Lo and 1 more

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Article in Acta Cardiologica Sinica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Ting-Wei Ernie LiaoSchool of Medicine, College of Medicine, National Yang Ming Chiao Tung University.
Li-Wei LoSchool of Medicine, College of Medicine, National Yang Ming Chiao Tung University.
Yenn-Jiang LinSchool of Medicine, College of Medicine, National Yang Ming Chiao Tung University.
Shih-Lin ChangSchool of Medicine, College of Medicine, National Yang Ming Chiao Tung University.
Yu-Feng HuSchool of Medicine, College of Medicine, National Yang Ming Chiao Tung University.
Fa-Po ChungSchool of Medicine, College of Medicine, National Yang Ming Chiao Tung University.
Tze-Fan ChaoSchool of Medicine, College of Medicine, National Yang Ming Chiao Tung University.
Jo-Nan LiaoSchool of Medicine, College of Medicine, National Yang Ming Chiao Tung University.
Hui-Wen YangInstitute of Translational and Interdisciplinary Medicine and Department of Biomedical Sciences and Engineering, National Central University, Taoyuan.
Men-Tzung LoInstitute of Translational and Interdisciplinary Medicine and Department of Biomedical Sciences and Engineering, National Central University, Taoyuan.
Shih-Ann ChenSchool of Medicine, College of Medicine, National Yang Ming Chiao Tung University.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Heart rate variability (HRV) provides insights beyond standard electrocardiography (ECG). Although prior studies have shown altered short-term linear HRV in patients with paroxysmal atrial fibrillation (PAF) after pulmonary vein isolation (PVI), long-term nonlinear changes are unclear. This study aimed to investigate longitudinal nonlinear HRV changes before and after PVI in PAF patients. Methods: Forty-two drug-refractory PAF patients (55.50 ± 9.53 years old, 11 females) undergoing PVI were enrolled. Holter ECG was recorded before, at 1-3 months, and at 6-12 months post-PVI. Nonlinear HRV variables including multi-scale entropy (MSE), detrended fluctuation analysis (DFA), and Poincaré plot analysis, were analyzed. Results: Significant reductions in standard deviation (SD)1, SD1/SD2, Conclusions: Long-term fractal correlation properties (

Indexed as

Atrial fibrillationDetrended fluctuation analysisHeart rate variabilityMultiscale entropyNonlinear heart rate variabilityPoincaré plot analysis

Identifiers

PMID42780719
PMCPMC13598606

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.