ArticleVeterinary medicine international2026
The Impact of Etomidate on Tear Secretion and Oxidative Stress Markers in Domestic Male Cats: A Clinical Study.
Article in Veterinary medicine international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
The aim of the present study was to evaluate the effects of etomidate on tear secretion and tear oxidative stress parameters, including total oxidant status (TOS), total antioxidant capacity (TAC), and Oxidative Stress Index (OSI), in domestic male cats. Thirty client-owned male domestic shorthair cats were enrolled in a prospective controlled clinical study and allocated to either an intervention group receiving etomidate (2 mg/kg intravenously) or a control group that did not receive any anesthetic or sedative drugs. Tear secretion and oxidative stress parameters were assessed at baseline (T0) and at 5 (T1), 10 (T2), and 15 (T3) minutes following etomidate administration in the intervention group and at corresponding observation time points in the control group using the Schirmer tear test. Tear production was significantly reduced in the etomidate-treated group at all postadministration time points compared to baseline (
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