Evidence map›Paper›PMID 42780667›Full record

ArticleBioactive materials2027

Multienzymatic hybrid bio-heterojunction for synergistic microenvironment reprogramming and selenoprotein-activated mitochondrial bioenergetics in diabetic osseointegration.

Meihua Zhang, Ming Lu, Yangrui Chen, Mengmeng Ming, Bin Luo, Yao Wu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioactive materials, 2027. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Meihua ZhangNational Engineering Research Center for Biomaterials, Sichuan University, Chengdu, 610064, PR China.
Ming LuNational Engineering Research Center for Biomaterials, Sichuan University, Chengdu, 610064, PR China.
Yangrui ChenNational Engineering Research Center for Biomaterials, Sichuan University, Chengdu, 610064, PR China.
Mengmeng MingNational Engineering Research Center for Biomaterials, Sichuan University, Chengdu, 610064, PR China.
Bin LuoAnalytical and Testing Center, Sichuan University, Chengdu, 610064, PR China.
Yao WuNational Engineering Research Center for Biomaterials, Sichuan University, Chengdu, 610064, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Regeneration of diabetic bone defects has always been a significant challenge in clinical treatment. The pathologic diabetic microenvironment, characterized by bacterial infection, excessive reactive oxygen species (ROS) generation, lactate accumulation, and chronic inflammation, triggers mitochondrial dysfunction and an energy metabolism crisis. To address this issue, we developed a synergistic multienzymatic bio-heterojunction (MoSe

Indexed as

Diabetic bone defectsMitochondrial bioenergeticsMitophagic fluxMultienzymatic bio-heterojunctionPathologic microenvironment

Identifiers

PMID42780667
PMCPMC13598597

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.