ArticleFrontiers in bioengineering and biotechnology2026
Exogenous electrical stimulation combined with electroactive nanopatches promotes cutaneous nerve regeneration and wound healing.
Article in Frontiers in bioengineering and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
High-quality skin wound healing requires rapid closure, complete re-epithelialization, orderly collagen remodeling, minimal scarring, and restoration of local sensory function. Substantial evidence confirms that peripheral nerve regeneration in the skin is not a passive concomitant of repair, but a critical foundation for functional tissue regeneration. However, effective combinatorial strategies to synchronously promote nerve regeneration and wound healing via a personalized electroactive microenvironment remain an unmet clinical need, driving the development of targeted electroactive biomaterials. In this study, an electroactive polycaprolactone/carbon nanotube (PCL/CNT) nanopatch was fabricated by electrospinning. Its microstructure and electroactivity were characterized, and the biosafety and efficacy of the patch combined with exogenous electrical stimulation (ES) were evaluated.
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