Evidence map›Paper›PMID 42780566›Full record

SynthesisFrontiers in medicine2026

Can acupuncture improve cardiac function in patients after percutaneous coronary intervention? A systematic review and meta-analysis.

Zhihong Chen, Jinna Nie, Jiangshan Tian

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zhihong ChenDepartment of Basic Medicine, Changchun University of Traditional Chinese Medicine, Changchun, Jilin, China.
Jinna NieDepartment of Basic Medicine, Changchun University of Traditional Chinese Medicine, Changchun, Jilin, China.
Jiangshan TianDepartment of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: To systematically evaluate the effects of acupuncture in improving cardiac function and the reported adverse events in patients after percutaneous coronary intervention (PCI) through meta-analysis. Methods: Electronic databases including PubMed, China National Knowledge Infrastructure, Wanfang Medical, China Biomedical Literature Database, VIP Database, Embase, Ovid Medline, Sinomed Database and the Cochrane Library were searched from inception to May 2026. Two reviewers independently screened the literature according to the inclusion and exclusion criteria and extracted data. The methodological quality was assessed using the Cochrane Handbook for Systematic Reviews of Interventions (version 5.1), and meta-analysis was performed with Review Manager 5.3. The evidence was appraised per the GRADE framework. Results: A total of 8 RCTs involving 759 patients were included, with 379 patients in the acupuncture group (247 males and 132 females) and 380 in the control group (conventional treatment or sham acupuncture; 257 males and 123 females). The results of the meta-analysis showed that, revealing that acupuncture was associated with better outcomes than conventional treatment or sham acupuncture in several measures. Specifically, the intervention led to a substantial boost in left ventricular ejection fraction (LVEF) by an average of 4.26 percentage points [95% CI (1.21, 7.31), Conclusion: Current evidence suggests that acupuncture may improve cardiac function in patients after PCI. However, the available literature is limited in both quantity and methodological quality. More rigorously designed, large-sample, high-quality RCTs are warranted to further validate these findings and provide more robust evidence for evidence-based practice. Systematic Review Registration: identifier CRD420261410954.

Indexed as

acupuncturecardiac functioncardiac remodelingmeta-analysispercutaneous coronary intervention (PCI)

Identifiers

PMID42780566
PMCPMC13597401

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.