Evidence map›Paper›PMID 42780447›Full record

ArticleMaterials today. Bio2026

NADPH-depletion micelles sensitizing apoptotic and ferroptotic cancer therapy under hypoxia.

Tianyuan Lei, Lefei Han, Yunan Zhang, Ningning Jiang, Dingding Deng, Xiu Wang, Qingqing Wang, Xuliang Guo

Abstract read
In one paragraph

Article in Materials today. Bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tianyuan LeiSchool of Pharmacy, Bengbu Medical University, Bengbu, 233000, PR China.
Lefei HanSchool of Pharmacy, Bengbu Medical University, Bengbu, 233000, PR China.
Yunan ZhangSchool of Pharmacy, Bengbu Medical University, Bengbu, 233000, PR China.
Ningning JiangSchool of Pharmacy, Bengbu Medical University, Bengbu, 233000, PR China.
Dingding DengSchool of Pharmacy, Bengbu Medical University, Bengbu, 233000, PR China.
Xiu WangSchool of Pharmacy, Bengbu Medical University, Bengbu, 233000, PR China.
Qingqing WangSchool of Pharmacy, Bengbu Medical University, Bengbu, 233000, PR China.
Xuliang GuoSchool of Pharmacy, Bengbu Medical University, Bengbu, 233000, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The heterogeneous characteristics of cancer determine that monotherapeutic strategies is difficult to deal with various sub-populations of cancer cells, leading to tumor recrudescence and dissemination. The combination of reactive oxygen species (ROS) mediated apoptosis in photodynamic therapy (PDT) and lipid peroxides induced ferroptosis exhibits remarkable potential in overcoming tumor heterogeneity-driven therapeutic resistance. However, the intracellular antioxidant systems involve the glutathione (GSH), reduced thioredoxin (Trx(SH)

Indexed as

ApoptosisFerroptosisNicotinamide adenine dinucleotide phosphate hydrogenPhotodynamic therapy

Identifiers

PMID42780447
PMCPMC13597287

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.