ArticleFrontiers in chemistry2026
Green CE-DAD determination of regulated aromatic amines in textiles through DoE optimization.
Article in Frontiers in chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Aromatic amines released from azo dyes are regulated in textile products under the European REACH framework due to their potential health risks. Their determination remains analytically challenging because of their structural similarity, moderate polarity, and the complexity of textile matrices, which can cause significant matrix effects. Methods: A green Capillary Electrophoresis method coupled with Diode Array Detection (CE-DAD) was developed for the simultaneous determination of eleven regulated aromatic amines in textile extracts. A Design of Experiments (DoE) approach was employed to systematically optimize the separation conditions, with the aim of maximizing resolution, selectivity, and robustness while minimizing analysis time. The environmental sustainability of the analytical procedure was assessed using the BAGI and Agree metric. Results: The optimized CE-DAD method showed satisfactory analytical performance when validated using spiked textile extracts, providing adequate recovery, precision, and robustness. The method also demonstrated good applicability to complex textile matrices. The green assessment confirmed the low environmental impact of the proposed analytical procedure. Conclusions: The developed CE-DAD method represents a sustainable, reliable, and cost-effective analytical strategy for the simultaneous determination and monitoring of regulated aromatic amines in textile products. The integration of DoE-based optimization and green analytical assessment highlights its potential as an environmentally responsible alternative for analysis of complex textile matrices.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.