Trial reportFrontiers in public health2026
Effects of acceptance and commitment therapy on fear of progression in young and middle-aged patients with breast cancer receiving particle therapy: a randomized controlled trial.
Trial report in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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7 authors.
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Abstract
Objective: Young and middle-aged patients with breast cancer receiving particle therapy commonly experience elevated Fear of Progression (FoP). Evidence for the effectiveness of acceptance and commitment therapy (ACT) in this population remains limited. This study evaluated the effects of ACT on FoP and on related psychological outcomes, namely psychological flexibility and psychological distress. Methods: This parallel-group randomized controlled trial was conducted at an oncology hospital in Shanghai, China, and enrolled participants between June and August 2025. A total of 108 young and middle-aged patients with breast cancer and elevated FoP (Fear of Progression Questionnaire-Short Form, FoP-Q-SF, ≥34) were randomly assigned in a 1:1 ratio to the intervention group ( Results: The overall attrition was 12%, and no intervention-related adverse events were identified. Compared with the control group, the intervention group showed greater reductions in FoP at all post-intervention time points (T1-T3, all Conclusion: Acceptance and commitment therapy reduced FoP and psychological distress in this population, with a delayed effect on psychological flexibility. These findings support integrating structured, group-based ACT into routine care during particle therapy. Multicenter trials with longer follow-up are needed. Trial registration: Chinese Clinical Trial Registry Identifier: ChiCTR2500104142.
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