Evidence map›Paper›PMID 42780259›Full record

ArticleResearch square2026

Discovery of the rosalexin pathway expands the modular network of maize diterpenoid phytoalexins.

Anna E Cowie, Gabrielle Wyatt, Siena Schumaker, Ahmed Khalil, Alicia Ross, Shamita Bhattacharjee, Jishnu Narayanan S J, Yezhang Ding, Elly Poretsky, David Hurd and 6 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in Research square, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Anna E CowieDepartment of Plant Biology, University of California-Davis, Davis, CA 95616, USA.
Gabrielle WyattDepartment of Plant Biology, University of California-Davis, Davis, CA 95616, USA.
Siena SchumakerDepartment of Plant Biology, University of California-Davis, Davis, CA 95616, USA.
Ahmed KhalilSection of Cell and Developmental Biology, University of California-San Diego, La Jolla, CA 92093, USA.ORCID 0000-0001-9384-8390
Alicia RossDepartment of Chemistry, University of California-Davis, Davis, CA 95616, USA.
Shamita BhattacharjeeDepartment of Plant Biology, University of California-Davis, Davis, CA 95616, USA.ORCID 0009-0008-8958-6242
Jishnu Narayanan S JDepartment of Chemistry and Institute for Nanotechnology and Advanced Materials, Bar Ilan University, Ramat Gan 5290002, Israel.
Yezhang DingSection of Cell and Developmental Biology, University of California-San Diego, La Jolla, CA 92093, USA.
Elly PoretskySection of Cell and Developmental Biology, University of California-San Diego, La Jolla, CA 92093, USA.
David HurdDepartment of Plant Biology, University of California-Davis, Davis, CA 95616, USA.
Jedidiah O PeekDepartment of Plant Biology, University of California-Davis, Davis, CA 95616, USA.ORCID 0009-0009-8440-2579
Alisa HuffakerSection of Cell and Developmental Biology, University of California-San Diego, La Jolla, CA 92093, USA.
Dean J TantilloDepartment of Chemistry, University of California-Davis, Davis, CA 95616, USA.ORCID 0000-0002-2992-8844
Dan T MajorDepartment of Chemistry and Institute for Nanotechnology and Advanced Materials, Bar Ilan University, Ramat Gan 5290002, Israel.ORCID 0000-0002-9231-0676
Eric A SchmelzSection of Cell and Developmental Biology, University of California-San Diego, La Jolla, CA 92093, USA.
Philipp ZerbeDepartment of Plant Biology, University of California-Davis, Davis, CA 95616, USA.ORCID 0000-0001-5163-9523

Funding

Understanding and manipulating biosynthetic mechanisms for formation of terpenes relevant to human healthR35GM153469 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Dean Tantillo · 2024 to 2026
$1.1M
NIGMS NIH HHS R35 GM153469
6 · The paper itself

Abstract

The evolutionary expansion of specialized metabolism has shaped the ability of plants to adapt to combined pest, disease, and environmental pressures. In maize (

Indexed as

BiochemistryBiological Sciencescytochrome P450 monooxygenasesditerpene synthasesphytoalexinsPlant Biologyplant-environment interactionsplant immunityplant specialized metabolismterpenoidsZea mays

Identifiers

PMID42780259
PMCPMC13596625

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.