Evidence map›Paper›PMID 42780231›Full record

ArticleResearch square2026

Role of

Callie J Zaborenko, Aaron Hakim, Tae-Hwi Schwantes-An, Harish Gopalakrishna, David E Kleiner, Marc G Ghany, Ruth M Pfeiffer, Chaowapong Jarasvaraparn, Tiebing Liang, Kung-Hung Lin and 5 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in Research square, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Callie J ZaborenkoIndiana University.
Aaron HakimBeth Israel Deaconess Medical Center.
Tae-Hwi Schwantes-AnIndiana University.
Harish GopalakrishnaNIDDK.
David E KleinerNational Cancer Institute.
Marc G GhanyNIDDK.
Ruth M PfeifferNational Cancer Institute.
Chaowapong JarasvaraparnIndiana University.
Tiebing LiangIndiana University.
Kung-Hung LinKaohsiung Medical University.
Ludmila Prokunina-OlssonNational Cancer Institute.
Eduardo Vilar-GomezIndiana University.
Niharika R SamalaIndiana University.
Naga ChalasaniIndiana University.
Thomas O'BrienNational Cancer Institute.

Funding

Continuation of the Non-Alcoholic Steatohepatitis Clinical Research Network (NASHU01DK061730 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI TONASCIA, JAMES A · 2002 to 2018
$23.2M
VEDS Year2-Continuation of the Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN) Data Coordinating CenterU24DK061730 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI JEANNE M CLARK, David M Shade · 2019 to 2026
$11.3M
Collaborative Clinical Research on Non Alcoholic StratohepatitisU01DK061737 · NIDDK · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI NAGA P CHALASANI · 2002 to 2026
$10.2M
NIDDK NIH HHS U01 DK061730NIDDK NIH HHS U01 DK061737NIDDK NIH HHS U24 DK061730
6 · The paper itself

Abstract

Background and Aims: In patients infected with hepatitis C virus, genetic polymorphisms within or near the interferon lambda 4 gene ( Approach and Results: Among 1786 non-Hispanic, white adults with biopsy-confirmed MASLD enrolled in the Nonalcoholic Steatohepatitis Clinical Research Network cohort (NASH CRN), the Conclusions: In contrast to some previous studies, this investigation of > 4,000 individuals provides no evidence that the

Indexed as

fatty liver diseasegeneticsIFNL4interferon lambda

Identifiers

PMID42780231
PMCPMC13596662

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.