Evidence map›Paper›PMID 42780228›Full record

ArticleFrontiers in public health2026

Autism spectrum disorder burden across 798 locations, 1990-2023: frontier and inequality mapping in the context of child injury prevention and safety promotion.

Xuezhi Liang, Wenyi Jin, Xinyan Bu, Minglu Yuan, Meng Zheng, Shiyu Feng, Liling Zhu, Yutong Lu, Jing-Xuan Zhou, Nadia M Hamdy and 5 more

Abstract read
In one paragraph

Article in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

15 authors.

Xuezhi Liang *Department of Medical Statistics, School of Public Health, Sun Yat-sen University, Guangzhou, China.
Wenyi Jin *Department of Orthopaedics, Renmin Hospital of Wuhan University, Wuhan University, Wuhan, China.
Xinyan BuDepartment of Medical Statistics, School of Public Health, Sun Yat-sen University, Guangzhou, China.
Minglu YuanDepartment of Medical Statistics, School of Public Health, Sun Yat-sen University, Guangzhou, China.
Meng ZhengDepartment of Medical Statistics, School of Public Health, Sun Yat-sen University, Guangzhou, China.
Shiyu FengDepartment of Medical Statistics, School of Public Health, Sun Yat-sen University, Guangzhou, China.
Liling ZhuGuangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Breast Tumor Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.
Yutong LuNational Supercomputer Center in Guangzhou, Sun Yat-sen University, Guangzhou, China.
Jing-Xuan ZhouSchool of Urban Planning and Design, Peking University Shenzhen Graduate School, Shenzhen, China.
Nadia M HamdyDepartment of Biochemistry, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt.
Claire Chenwen ZhongJC School of Public Health & Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, Hong Kong SAR, China.
Queran LinGuangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Breast Tumor Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.
Xiaoliang HuangGovernment Affairs Service Centre of Health Commission of Guangdong Province, Guangzhou, China.
Wen ChenDepartment of Medical Statistics, School of Public Health, Sun Yat-sen University, Guangzhou, China.
GBD Child Autism Injury Collaborators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Autism spectrum disorder (ASD) is commonly identified in childhood and can affect communication, adaptive functioning, supervision, and access to health and educational services. These needs may be relevant to child safety planning, but this study did not measure injury outcomes. Methods: We analyzed Global Burden of Disease 1990-2023 estimates of ASD incidence and disability-adjusted life-year (DALY) rates across 798 locations. Age-standardized and under-20 rates were benchmarked against a Socio-demographic Index-related frontier using free disposal hull analysis. Socioeconomic inequalities were assessed using the slope index of inequality and concentration index. Results: In 2023, 98 countries and territories (48.0%) were classified as behind the age-standardized incidence frontier and 78 (38.2%) as behind the age-standardized DALY frontier. Among individuals younger than 20 years, 100 (49.0%) were behind the incidence frontier and 123 (60.2%) were behind the DALY frontier. Frontier deviation increased in most countries between 1990 and 2023. Sweden had the largest reduction across all four national metrics, whereas Japan had the largest increase. Japan also had the largest 2023 deviations for age-standardized incidence, age-standardized DALYs, and under-20 DALYs; Brunei Darussalam had the largest under-20 incidence deviation. Selected Japanese prefectures were prominent subnational outliers, while locations in Pakistan and Nigeria showed the largest reductions. Recorded under-20 DALY burden became more concentrated in higher-SDI populations globally, whereas disadvantaged populations within low-SDI settings retained substantial absolute inequality. Discussion: These findings provide descriptive benchmarks for ASD surveillance, early recognition, service organization, and equitable healthcare planning. They should not be interpreted as direct measures of service quality, unmet need, or injury risk.

Indexed as

Autism Spectrum DisorderHealth PromotionWounds and InjuriesAdolescentChildChild, PreschoolDisability-Adjusted Life YearsFemaleGlobal Burden of DiseaseGlobal HealthHumansIncidenceMaleSocioeconomic Disparities in Healthautism Spectrum disorderchild injury preventionhealth inequalitysafety promotionsubnational analysis

Identifiers

PMID42780228
PMCPMC13597694

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.