ArticleResearch square2026
Cerebellar High Frequency Transcranial Pulsed Current Stimulation Increases Total Sleep Time in Chronic Insomnia: A Pilot Study.
Article in Research square, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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10 authors.
Funding
Abstract
Chronic insomnia is characterized by reduced sleep duration and is associated with substantial physical and psychological morbidity. Existing treatments are limited by accessibility, tolerability, and persistent residual symptoms. Given emerging evidence implicating the cerebellum in sleep-wake regulation, we evaluated the safety and efficacy of cerebellar high-frequency transcranial pulsed current stimulation (tPCS) in individuals with chronic insomnia. In this double-blind, randomized, sham-controlled pilot trial, thirty adults on stable pharmacotherapy were assigned 1: 1 to receive 12 sessions of bilateral cerebellar active tPCS (400 Hz, 0.6 mA average current, 30 minutes/session) or sham stimulation over two weeks. The primary outcome was actigraphy-derived total sleep time (TST). Between-group comparisons were performed using rank analysis of covariance adjusting for baseline values. Compared with sham stimulation, active tPCS significantly increased TST (adjusted mean difference, 34.25 minutes; 95% CI, 1.60-66.89; Trial Registration: Chinese Clinical Trial Registry ChiCTR2300072403, Date of registration: Jun 12, 2023; (URL: https://www.chictr.org.cn/showproj.html?proj=199226).
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