Evidence map›Paper›PMID 42780203›Full record

ArticlebioRxiv : the preprint server for biology2026

Antibiotics modulate activity of mouse and human dorsal root ganglia neurons.

Ashley N Plumb, Joseph B Lesnak, Jane M Brandon, Lucia M Cardona, Mackenzie A Simms, McKenna L Pratt, Katie T Ward, Kevin J Tidgewell, Gregory Dussor, Theodore J Price and 1 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ashley N PlumbDepartment of Neuroscience, Center for Advanced Pain Studies, University of Texas at Dallas, Richardson, TX 75080, USA.ORCID 0000-0002-8566-4943
Joseph B LesnakDepartment of Neuroscience, Center for Advanced Pain Studies, University of Texas at Dallas, Richardson, TX 75080, USA.ORCID 0000-0002-4098-9090
Jane M BrandonDepartment of Neuroscience, Center for Advanced Pain Studies, University of Texas at Dallas, Richardson, TX 75080, USA.ORCID 0009-0008-3253-0272
Lucia M CardonaDepartment of Neuroscience, Center for Advanced Pain Studies, University of Texas at Dallas, Richardson, TX 75080, USA.
Mackenzie A SimmsDepartment of Neuroscience, Center for Advanced Pain Studies, University of Texas at Dallas, Richardson, TX 75080, USA.ORCID 0009-0004-3087-8700
McKenna L PrattDepartment of Neuroscience, Center for Advanced Pain Studies, University of Texas at Dallas, Richardson, TX 75080, USA.
Katie T WardDepartment of Pharmaceutical Sciences, University of Kentucky, Lexington, KY 40506, USA.
Kevin J TidgewellDepartment of Pharmaceutical Sciences, University of Kentucky, Lexington, KY 40506, USA.ORCID 0000-0002-0501-2604
Gregory DussorDepartment of Neuroscience, Center for Advanced Pain Studies, University of Texas at Dallas, Richardson, TX 75080, USA.
Theodore J PriceDepartment of Neuroscience, Center for Advanced Pain Studies, University of Texas at Dallas, Richardson, TX 75080, USA.ORCID 0000-0002-6971-6221
Katelyn E SadlerDepartment of Neuroscience, Center for Advanced Pain Studies, University of Texas at Dallas, Richardson, TX 75080, USA.ORCID 0000-0003-2078-3527

Funding

Mechanistic underpinnings of chronic low back painU19NS130608 · NINDS · UNIVERSITY OF TEXAS DALLAS · PI Diana Tavares Ferreira · 2022 to 2026
$13.6M
Sickle cell disease gut dysbiosis effects on CNS pain processingR00HL155791 · NHLBI · UNIVERSITY OF TEXAS DALLAS · PI SADLER, KATELYN · 2023 to 2025
$747k
Gut Microbiome Targets for Sickle Cell Disease Pain ManagementR01HL181083 · NHLBI · UNIVERSITY OF TEXAS DALLAS · PI Katelyn Sadler · 2026 to 2026
$642k
Vaginal microbiome-nociceptor interactions in endometriosis painR01HD121726 · NICHD · UNIVERSITY OF TEXAS DALLAS · PI Katelyn Sadler · 2026 to 2026
$608k
NHLBI NIH HHS R00 HL155791NHLBI NIH HHS R01 HL181083NICHD NIH HHS R01 HD121726NINDS NIH HHS U19 NS130608
6 · The paper itself

Abstract

Antibiotics are among the most prescribed medications worldwide, yet their direct effects on eukaryotic tissues remain largely unexplored. Here, we used

Identifiers

PMID42780203
PMCPMC13596543

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.