ArticleFrontiers in nutrition2026
Leisure-related sedentary time and physical activity with myocardial infarction incidence: a prospective cohort study.
Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: This study aimed to comprehensively investigate the associations between leisure-related sedentary time, physical activity (PA), and the incidence of myocardial infarction (MI) and its subtypes. Methods: This cohort study included 475,874 individuals free of MI at baseline. Daily behavioral data-including leisure-related sedentary time, PA, and sleep duration-along with baseline demographic characteristics were collected. Three multivariable-adjusted Cox proportional hazards models were constructed to assess the association between leisure-related sedentary time and incident MI. Additionally, a mutually adjusted Cox model incorporating all four behaviors simultaneously was used to estimate hazard ratios for inter-behavior comparisons via coefficient contrasts, evaluating whether higher PA or sleep durations, independent of other measured behaviors, were associated with reduced MI risk. Results: Compared with the reference group, individuals with leisure-related sedentary time exceeding 4 h per day had an increased risk of MI and its subtypes after full multivariable adjustment. Mutually adjusted analyses demonstrated inverse associations with MI risk across all behaviors. Coefficient contrasts indicated that a 60-min higher duration of sleep, LPA, or MVPA-holding other measured behaviors constant-corresponded to hazard ratios of 0.967 (95% CI: 0.954-0.980) for sleep, 0.987 (95% CI: 0.964-1.011) for LPA, and 0.974 (95% CI: 0.953-0.995) for MVPA. Consistent patterns were observed for 30-min and 15-min contrasts, with estimated risk reductions ranging from approximately 1-6% across all comparisons. Conclusion: Prolonged leisure-related sedentary time is associated with an increased risk of MI, STEMI, and NSTEMI. Independent of other daily behaviors, higher durations of PA and sleep are inversely associated with MI incidence, with benefits evident even at modest (15-30 min) differences in daily duration.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.