Evidence map›Paper›PMID 42780086›Full record

ArticlebioRxiv : the preprint server for biology2026

Variation in multiple classes of simple sequence repeats can alter drug susceptibility in

Peter O Oluoch, Michael J Luna, Gavin Fujimori, Mayashree Das, Roger Vargas, Kadamba G Papavinasasundaram, Maha R Farhat, Christopher M Sassetti

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Peter O OluochDepartment of Microbiology, University of Massachusetts Medical School, Worcester, Massachusetts, 01655, USA.ORCID 0000-0001-7451-4993
Michael J LunaDepartment of Microbiology, University of Massachusetts Medical School, Worcester, Massachusetts, 01655, USA.
Gavin FujimoriDepartment of Microbiology, University of Massachusetts Medical School, Worcester, Massachusetts, 01655, USA.
Mayashree DasDepartment of Microbiology, University of Massachusetts Medical School, Worcester, Massachusetts, 01655, USA.
Roger VargasDepartment of Biomedical Informatics, Harvard Medical School, 25 Shattuck St., Boston, MA, 02115, USA.
Kadamba G PapavinasasundaramDepartment of Microbiology, University of Massachusetts Medical School, Worcester, Massachusetts, 01655, USA.
Maha R FarhatDepartment of Biomedical Informatics, Harvard Medical School, 25 Shattuck St., Boston, MA, 02115, USA.ORCID 0000-0002-3871-5760
Christopher M SassettiDepartment of Microbiology, University of Massachusetts Medical School, Worcester, Massachusetts, 01655, USA.

Funding

Surviving evolution: Short-term adaptations for fitnessP01AI143575 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI SABINE EHRT · 2020 to 2026
$18.2M
NIAID NIH HHS P01 AI143575
6 · The paper itself

Abstract

Insertions and deletions (INDELs) in simple sequence repeats (SSRs) generate relatively high-frequency reversible genetic changes that facilitate bacterial adaptation to changing environments. Analyses of global

Indexed as

intermediate antibiotic resistanceMycobacterium tuberculosissimple sequence repeatstriplet repeats

Identifiers

PMID42780086
PMCPMC13596474

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.