Evidence map›Paper›PMID 42779973›Full record

ArticlebioRxiv : the preprint server for biology2026

Computational design of potent, broadly neutralizing anti-Nipah virus and Hendra virus miniproteins.

Jeremiah N Sims, Risako Gen, Kaitlin Sprouse, Young-Jun Park, Zhaoqian Wang, Moushimi Amaya, Alka Jays, Brendan B Larsen, Cameron Stewart, Jack T Brown and 9 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Jeremiah N SimsInstitute for Protein Design, University of Washington, Seattle, WA 98105, USA.ORCID 0000-0002-0479-0367
Risako GenDepartment of Biochemistry, University of Washington, Seattle, WA 98195, USA.ORCID 0009-0004-4416-0417
Kaitlin SprouseHoward Hughes Medical Institute, University of Washington, Seattle, WA 98105, USA.ORCID 0000-0003-0007-2226
Young-Jun ParkHoward Hughes Medical Institute, University of Washington, Seattle, WA 98105, USA.
Zhaoqian WangDepartment of Biochemistry, University of Washington, Seattle, WA 98195, USA.ORCID 0000-0001-8989-0422
Moushimi AmayaDepartment of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, USA.
Alka JaysDepartment of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, USA.ORCID 0009-0003-7287-1219
Brendan B LarsenBasic Sciences Division and Computational Biology Program, Fred Hutch Cancer Center, Seattle, WA 98109, USA.
Cameron StewartDepartment of Biochemistry, University of Washington, Seattle, WA 98195, USA.
Jack T BrownDepartment of Biochemistry, University of Washington, Seattle, WA 98195, USA.
Robert RagotteInstitute for Protein Design, University of Washington, Seattle, WA 98105, USA.ORCID 0000-0002-6463-1595
Rashmi RavichandranInstitute for Protein Design, University of Washington, Seattle, WA 98105, USA.ORCID 0000-0002-2630-7487
Garrett RuthInstitute for Protein Design, University of Washington, Seattle, WA 98105, USA.ORCID 0009-0004-4974-0410
Xinting LiInstitute for Protein Design, University of Washington, Seattle, WA 98105, USA.ORCID 0000-0001-5559-7578
Dionne VafeadosInstitute for Protein Design, University of Washington, Seattle, WA 98105, USA.ORCID 0000-0002-2560-8907
Jesse D BloomHoward Hughes Medical Institute, University of Washington, Seattle, WA 98105, USA.ORCID 0000-0003-1267-3408
Christopher BroderDepartment of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, USA.ORCID 0000-0001-5382-0510
David VeeslerDepartment of Biochemistry, University of Washington, Seattle, WA 98195, USA.ORCID 0000-0002-6019-8675
David BakerInstitute for Protein Design, University of Washington, Seattle, WA 98105, USA.ORCID 0000-0001-7896-6217

Funding

RP5: Nanobody therapeutics against henipaviruses, arenaviruses, and structural characterizationU19AI181930 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI BRODER, CHRISTOPHER C, GEISBERT, THOMAS WILLIAM · 2024 to 2024
$46.4M
Project 5: mRNA and mRNA-launched nanoparticle vaccinesU19AI181881 · NIAID · UNIVERSITY OF WASHINGTON · PI KING, NEIL, STUART, LYNDA · 2024 to 2024
$41.1M
Project 3 - USUHSU19AI142764 · NIAID · HENRY M. JACKSON FDN FOR THE ADV MIL/MED · PI BRODER, CHRISTOPHER C · 2019 to 2023
$24.6M
Centers for Research on Structural Biology of Infectious Diseases: Universal Influenza Vaccine Research75N93022C00036 · NIAID · SEATTLE CHILDREN'S HOSPITAL · PI STAKER, BART · 2022 to 2025
$21.7M
Unraveling the bat humoral immune response against zoonotic viruses to guide the design of next-generation therapeuticsDP1AI158186 · NIAID · UNIVERSITY OF WASHINGTON · PI VEESLER, DAVID · 2020 to 2024
$5.4M
NIAID NIH HHS DP1 AI158186NIAID NIH HHS U19 AI142764NIAID NIH HHS U19 AI181881NIAID NIH HHS U19 AI181930NIH HHS 75N93022C00036
6 · The paper itself

Abstract

The prototype members of the genus

Identifiers

PMID42779973
PMCPMC13596370

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.