Evidence map›Paper›PMID 42779928›Full record

ArticlebioRxiv : the preprint server for biology2026

An in vivo chemical genetic approach for targeted glycoproteome analysis in

Sophie D Schmidt, Cyrille Alexandre, Lucia Di Vagno, Liping Zhang, Helen Flynn, Joachim Kurth, Steve Murray, Sasha Ruiz Herrera, Hannah Shaw, Ganka Bineva-Todd and 6 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Sophie D SchmidtChemical Glycobiology Laboratory, The Francis Crick Institute, NW1 1AT London, United Kingdom.
Cyrille AlexandreEpithelial Cell Interactions Laboratory, The Francis Crick Institute, NW1 1AT London, United Kingdom.
Lucia Di VagnoChemical Glycobiology Laboratory, The Francis Crick Institute, NW1 1AT London, United Kingdom.
Liping ZhangDevelopmental Glycobiology Section, NIDCR, National Institutes of Health, 30 Convent Drive, Bethesda, Maryland 20892.
Helen FlynnProteomics Science Technology Platform, The Francis Crick Institute, NW1 1AT London, United Kingdom.
Joachim KurthFly Facility, The Francis Crick Institute, NW1 1AT London, United Kingdom.
Steve MurrayFly Facility, The Francis Crick Institute, NW1 1AT London, United Kingdom.
Sasha Ruiz HerreraFly Facility, The Francis Crick Institute, NW1 1AT London, United Kingdom.
Hannah ShawFly Facility, The Francis Crick Institute, NW1 1AT London, United Kingdom.
Ganka Bineva-ToddChemical Glycobiology Laboratory, The Francis Crick Institute, NW1 1AT London, United Kingdom.
Ömür Y TastanChemical Glycobiology Laboratory, The Francis Crick Institute, NW1 1AT London, United Kingdom.
Mark SkehelProteomics Science Technology Platform, The Francis Crick Institute, NW1 1AT London, United Kingdom.
Nadine L SamaraStructural Biochemistry Unit, National Institute of Dental and Craniofacial Research, NIH, Bethesda, MD, 20892, USA.
Kelly G Ten HagenDevelopmental Glycobiology Section, NIDCR, National Institutes of Health, 30 Convent Drive, Bethesda, Maryland 20892.
Jean-Paul VincentEpithelial Cell Interactions Laboratory, The Francis Crick Institute, NW1 1AT London, United Kingdom.ORCID 0000-0003-2305-5744
Benjamin SchumannChemical Glycobiology Laboratory, The Francis Crick Institute, NW1 1AT London, United Kingdom.ORCID 0000-0001-5504-0147

Funding

Structural and functional studies of polypeptide N-acetylgalactosaminyltransferases (GalNAc-Ts)ZIADE000754 · NIDCR · NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH · PI SAMARA, NADINE · 2020 to 2025
$4.0M
Role of O-glycosylation in Animal DevelopmentZ01DE000713 · NIDCR · NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH · PI TEN HAGEN, KELLY G · 2006 to 2008
$2.0M
Intramural NIH HHS Z01 DE000713Intramural NIH HHS ZIA DE000754Wellcome Trust CC2127Wellcome Trust FC001204
6 · The paper itself

Abstract

Glycans impact every aspect of physiology. Despite the rapid increase in relevance and translational potential, there remains a lack of tools for studying glycosylation

Identifiers

PMID42779928
PMCPMC13596352

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.