ArticlebioRxiv : the preprint server for biology2026
The small molecule regacin binds a conserved pocket in RegA to inhibit the expression of bacterial virulence factors.
Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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0 citing papers in PubMed.
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Authors and funding
6 authors.
Funding
Abstract
Widespread antibiotic resistance is an urgent threat to public health. Small molecules that specifically target virulence factors or their expression are promising alternative therapeutics to antibiotics. The small molecule regacin was identified as a potent inhibitor of RegA, a transcription factor required for the expression of numerous virulence genes of
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.