ArticleChildhood kidney diseases2025
Comparison of various prediction equations for glomerular filtration rate in Korean pediatric cancer patients: a retrospective study.
Article in Childhood kidney diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Purpose: Assessment of kidney function is essential in the management and follow-up of children with cancer. However, the best method to assess the kidney function in children with cancer is unknown. Methods: The study compared glomerular filtration rate (GFR) using various methods. Four methods for determining GFR are as follows: technetium-99m diethylenetriaminepentaacetic acid clearance (mGFR), serum creatinine (sCr)-based equations (eGFR-Schwartz and eGFR-Pottel), cystatin C (CysC)-based equations (eGFR-Zappitelli1 and eGFR-CKiD1), and combined sCr-CysC-based equations (eGFR-Zappitelli2 and eGFR-CKiD2). Results: A total of 54 pediatric patients diagnosed with cancer were evaluated. The estimated GFR (eGFR) equations showed moderately correlated with mGFR, with eGFR-Zappitelli2 showing the highest correlation ( Conclusions: Among the methods evaluated, the combined sCr-CysC-based eGFR showed better accuracy with mGFR compared with the other equations in children with cancer.
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