Evidence map›Paper›PMID 42779640›Full record

ArticlebioRxiv : the preprint server for biology2026

Cellular source and circuit context organize functional specificity in the

Madison N Endres, Tarandeep Singh Dadyala, Kevin W Christie, Irina T Sinakevitch, Lisha Shao

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Madison N EndresDepartment of Biological Sciences, University of Delaware, 105 The Green, Newark, DE 19716.
Tarandeep Singh DadyalaDepartment of Biological Sciences, University of Delaware, 105 The Green, Newark, DE 19716.
Kevin W ChristieDepartment of Biological Sciences, University of Delaware, 105 The Green, Newark, DE 19716.
Irina T SinakevitchDepartment of Biological Sciences, University of Delaware, 105 The Green, Newark, DE 19716.
Lisha ShaoDepartment of Biological Sciences, University of Delaware, 105 The Green, Newark, DE 19716.

Funding

Predictive Modeling & Optimal Control Framework for Model-Based Epidemic Response in DelawareP20GM103446 · NIGMS · UNIVERSITY OF DELAWARE · PI Shawn W Polson · 2012 to 2026
$67.2M
Subproject Title: Clinical Research Education, Mentoring and Career Development CoreU54GM104941 · NIGMS · UNIVERSITY OF DELAWARE · PI Susan Poland Giancola · 2013 to 2026
$60.5M
Crowdsourcing the Fly ConnectomeRF1MH117815 · NIMH · PRINCETON UNIVERSITY · PI MURTHY, MALA, SEUNG, HYUNJUNE SEBASTIAN · 2018 to 2018
$3.3M
Elucidating the molecular and neural structure of female sexual rewardR35GM147504 · NIGMS · UNIVERSITY OF DELAWARE · PI Lisha Shao · 2022 to 2026
$2.0M
NIGMS NIH HHS P20 GM103446NIGMS NIH HHS R35 GM147504NIGMS NIH HHS U54 GM104941NIMH NIH HHS RF1 MH117815
6 · The paper itself

Abstract

Neuropeptides regulate diverse and sometimes opposing functions, yet how a single peptide achieves functional specificity remains unclear. Receptor diversity can provide specificity, but not in systems with only one receptor.

Identifiers

PMID42779640
PMCPMC13596182

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.