ArticleChildhood kidney diseases2026
Trends in antibiotic susceptibility in childhood acute urinary tract infections: a single-center comparison across a 10-year interval in Korea.
Article in Childhood kidney diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Purpose: Acute urinary tract infection (UTI) is one of the most common bacterial infections in children and a major cause of antibiotic use. Increasing antimicrobial resistance has raised concerns regarding the appropriate selection of empirical antibiotics in pediatric UTIs. Methods: We retrospectively analyzed 571 children diagnosed with culture-confirmed acute UTI at a single tertiary center between 2015 and 2020 and compared the findings with data from a previous study conducted at the same institution between 2003 and 2008. Uropathogen distribution, antibiotic susceptibility patterns, extended-spectrum β-lactamase (ESBL) prevalence, and imaging findings were evaluated. Results: Gram-negative organisms accounted for 98.2% of UTIs, with Conclusions: Antibiotic resistance in pediatric UTIs increased significantly over an approximately 10-year period within the same institutional setting. These findings highlight evolving antimicrobial resistance and underscore the importance of continuous local surveillance to guide empirical antibiotic selection.
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