ArticlePediatric pulmonology2026
Congenital Lung Malformations in Neonates: A 9-Year Tunisian Cohort Highlighting Diagnostic Challenges and Outcomes in a Resource-Limited Setting.
Article in Pediatric pulmonology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundCongenital lung malformations (CLMs) represent a broad spectrum of developmental anomalies with highly variable prenatal and postnatal presentations and outcomes. Their postnatal management remains non-standardized. This study aimed to describe the spectrum of bronchopulmonary malformations diagnosed in the neonatal period, assess the contribution of antenatal and postnatal imaging, and characterize their clinical course and management in a resource-limited setting.
methodsWe conducted a retrospective descriptive study in the Intensive Care Unit of the Maternity and Neonatology Centre of Tunis, over a 9-year period. All newborns diagnosed with CLMs were included. Data were collected from obstetric, neonatal, and pediatric surgery records.
resultsTwenty-three newborns were included (prevalence: 0.23 per 1000 live births; M/F ratio: 0.91). The mean gestational age was 37.5 ± 2.9 weeks, and mean birth weight 2901 ± 833 g. Antenatal diagnosis was achieved in 65% of cases (
conclusionsWhile symptomatic CLMs in resource-limited settings carry significant early mortality due to system-level constraints, active conservative surveillance was associated with favorable outcomes in selected asymptomatic patients in this cohort when supported by structured parental education.
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