ArticleEuropean journal of breast health2026
Primary Merkel Cell Carcinoma of the Breast - A Report of an Extremely Rare Case.
Article in European journal of breast health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neuroendocrine carcinoma of the breast is a very rare malignancy, and when it presents with characteristics similar to Merkel cell carcinoma (MCC), it is even more uncommon. This report discusses a case of small cell carcinoma exhibiting Merkel cell-like features in an 80-year-old woman who had a history of rheumatoid arthritis under treatment with immunosuppressive drugs. Microscopic analysis showed tissue fragments with areas of necrosis, as well as focal regions containing neoplastic cells. These cells were small to medium in size, with poorly defined borders, scant cytoplasm, and hyperchromatic, atypical nuclei. Immunohistochemical staining revealed perinuclear (dot-like) positivity for cytokeratin 18/8 and strong positivity for cytokeratin 20 and cluster of differentiation 56. The cell proliferation marker Ki-67 was positive in over 80% of the cells. What is extremely rare in this case is the presentation of MCC of the breast as a retro areolar lesion, located behind the areola and associated with nipple discharge, without evidence of a primary cutaneous lesion.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.