Evidence map›Paper›PMID 42779088›Full record

ArticleThe American journal of case reports2026

Giant Well-Differentiated Liposarcoma of the Spermatic Cord Associated With Inguinal Hernia: Clinical Insights From a Case Report.

Kristian Chrz, David Hoskovec, Zdeněk Krška, M E Dämmrich, Pavol Klobušický

Abstract readCase Reports
In one paragraph

Article in The American journal of case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kristian Chrz1st Surgical Department, General University Hospital, Prague, Czech Republic.ORCID 0000-0003-3029-0574
David Hoskovec1st Surgical Department, General University Hospital, Prague, Czech Republic.ORCID 0000-0003-2948-8989
Zdeněk Krška1st Surgical Department, General University Hospital, Prague, Czech Republic.ORCID 0000-0002-1766-7472
M E DämmrichDiagnostic Network in Pathology, Schweinfurt, Germany.
Pavol Klobušický1st Medical Faculty, Charles University, Prague, Czech Republic.ORCID 0000-0001-9482-3646

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND Spermatic cord liposarcoma is a rare adipocytic malignancy, with fewer than 200 cases described worldwide. Due to its rarity and nonspecific clinical presentation, it is frequently misdiagnosed as more common inguinoscrotal conditions such as hernia or hydrocele. Histologically, liposarcomas comprise several subtypes with varying prognoses. Accurate diagnosis is often challenging preoperatively and typically relies on imaging and definitive histopathological evaluation. CASE REPORT We present the case of an 87-year-old man with a progressively enlarging, painless mass in the left inguinoscrotal region, significantly impairing mobility. Computed tomography revealed a large, well-circumscribed mass originating from the spermatic cord, with both cystic and fatty components, along with a concurrent inguinal hernia and hydrocele. No metastatic spread was identified. The patient underwent complete surgical excision of the tumor with simultaneous orchiectomy and inguinal herniotomy. Histopathological analysis confirmed a well-differentiated liposarcoma (G1) with negative surgical margins (R0 resection). Given the patient's advanced age and comorbidities, no adjuvant therapy was indicated. The postoperative course was uneventful. CONCLUSIONS Spermatic cord liposarcoma remains a diagnostic and therapeutic challenge due to its rarity and clinical resemblance to benign conditions. Radical surgical excision with negative margins is the cornerstone of treatment and offers favorable outcomes, particularly in well-differentiated, low-grade tumors. However, the high rate of local recurrence necessitates long-term follow-up. The role of adjuvant therapies such as radiotherapy or chemotherapy remains unclear and should be individualized based on tumor characteristics. Increased awareness and reporting of such cases are essential to improve diagnostic accuracy and optimize management strategies.

Indexed as

Genital Neoplasms, MaleHernia, InguinalLiposarcomaSpermatic CordAged, 80 and overDiagnosis, DifferentialHumansMaleOrchiectomyTomography, X-Ray Computed

Identifiers

PMID42779088
PMCPMC13621879

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.