Evidence map›Paper›PMID 42778906›Full record

Observational studyBMC public health2026

The NorthMom study: population-based follow-up of women in a birth cohort to assess pregnancy exposures and effects on breast cancer risk factors.

Alice Fredriksson, Richard Lundberg-Ulfsdotter, Marie-Therese Vinnars, Anna Oudin, Bethany Van Guelpen, Christina E West, Magnus Domellöf, Wendy Yi-Ying Wu, Karin Dembrower, Sophia Harlid

Abstract readObservational Study
In one paragraph

Observational study in BMC public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alice FredrikssonDepartment of Diagnostics and Intervention, Oncology, Umeå University, Umeå, 90187, Sweden.
Richard Lundberg-UlfsdotterDepartment of Clinical Sciences, Pediatrics, Umeå University, Umeå, Sweden.
Marie-Therese VinnarsDepartment of Clinical Sciences, Obstetrics and Gynecology, Umeå University, Umeå, Sweden.
Anna OudinDepartment of Epidemiology and Global Health, Umeå University, Umeå, Sweden.
Bethany Van GuelpenDepartment of Diagnostics and Intervention, Oncology, Umeå University, Umeå, 90187, Sweden.
Christina E WestDepartment of Clinical Sciences, Pediatrics, Umeå University, Umeå, Sweden.
Magnus DomellöfDepartment of Clinical Sciences, Pediatrics, Umeå University, Umeå, Sweden.
Wendy Yi-Ying WuDepartment of Diagnostics and Intervention, Oncology, Umeå University, Umeå, 90187, Sweden.
Karin Dembrower *Breast Imaging Unit, Department of Radiology, Capio Sankt Göran Hospital, Sankt Göransplan, Stockholm, Sweden. karin.dembrower@ki.se.
Sophia Harlid *Department of Diagnostics and Intervention, Oncology, Umeå University, Umeå, 90187, Sweden. sophia.harlid@umu.se.ORCID http://orcid.org/0000-0001-8540-6891

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe NorthMom Study (NorthMom) is an observational, population-based cohort designed to determine how the environment during pregnancy affects later health risks among women. The specific focus of NorthMom is breast cancer risk, evaluated through intermediate markers such as breast density, and additional outcomes may be studied in the future.

methodsNorthMom is nested in the larger NorthPop Birth Cohort Study (NorthPop), which was initiated in Västerbotten County, Sweden in 2016 and closed recruitment in 2025. All women previously enrolled in NorthPop are invited to join NorthMom after turning 40 years of age. Women who have moved from the county, have withdrawn or declined follow-up from NorthPop, or are pregnant at the time of invitation are considered ineligible. Those who agree to participate visit the Clinical Research Center at the University Hospital of Umeå in Västerbotten, Sweden. A study nurse collects a blood sample and additional health data, including body composition by Dual-Energy X-ray absorptiometry (DXA). To assess breast density, mammographic images from the Swedish national breast cancer screening program are acquired and evaluated both manually (by a consultant radiologist) and automatically using the Laboratory for Individualized Breast Radiodensity Assessment (LIBRA) software. Measures include classification according to BI-RADS 4 (1-4) and BI-RADS 5 (A-D), as well as continuous densities (%) and dense area (cm DISCUSSION: Analysis of data collected as part of NorthMom and NorthPop will be used to assess relationships between environmental exposures during pregnancy and women's later health, with a focus on breast cancer risk factors such as breast density after age 40.

trial registrationRegistered in Researchweb, 19 August 2026 (project number 287619).

Indexed as

Breast NeoplasmsPrenatal Exposure Delayed EffectsAdultBirth CohortBreast DensityFemaleFollow-Up StudiesHumansMiddle AgedPregnancyRisk FactorsSwedenBreast cancer riskEnvironmental exposuresEpidemiologyMammographic breast densityNorthMomNorthPopPregnancyRisk factorsWomen’s health

Identifiers

PMID42778906
PMCPMC13602515

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.