Evidence map›Paper›PMID 42778834›Full record

ArticleJournal of occupational rehabilitation2026

Economic Evaluation of an Indicated Prevention Strategy Focused on Future Long-Term Sickness Absence.

Sophie Klasen, Ludovic G P M van Amelsvoort, IJmert Kant, Nicole W H Jansen, Silvia M A A Evers

Abstract read
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In one paragraph

Article in Journal of occupational rehabilitation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sophie KlasenDepartment of Epidemiology, Care and Public Health Research Institute (CAPHRI), Maastricht University, P.O. Box 616, 6200 MD, Maastricht, The Netherlands.ORCID http://orcid.org/0000-0001-7806-1004
Ludovic G P M van AmelsvoortDepartment of Epidemiology, Care and Public Health Research Institute (CAPHRI), Maastricht University, P.O. Box 616, 6200 MD, Maastricht, The Netherlands. LGPM.vanamelsvoort@maastrichtuniversity.nl.ORCID https://orcid.org/0000-0003-0120-1552
IJmert KantDepartment of Epidemiology, Care and Public Health Research Institute (CAPHRI), Maastricht University, P.O. Box 616, 6200 MD, Maastricht, The Netherlands.ORCID http://orcid.org/0000-0002-6985-5264
Nicole W H JansenDepartment of Epidemiology, Care and Public Health Research Institute (CAPHRI), Maastricht University, P.O. Box 616, 6200 MD, Maastricht, The Netherlands.ORCID http://orcid.org/0000-0001-6463-5230
Silvia M A A EversDepartment of Health Services Research, Maastricht University, Maastricht, the Netherlands.ORCID http://orcid.org/0000-0003-1026-570X

Funding

Netherlands Organization for Health Research and Development (ZonMw) 505312598027
6 · The paper itself

Abstract

purposeAn indicated prevention strategy (IPS) targeting long-term sickness absence risk showed its effectiveness in a randomized controlled trial (RCT). To compare its costs and benefits with other preventive strategies within occupational health, an economic evaluation is essential.

methodsAn economic evaluation was conducted from the employer, healthcare, and societal perspectives. RCT data was used regarding the IPS efficacy, with additional collected data, covering 12 months of follow-up. The intervention group received an early intervention (n=132), and the care-as-usual group received care upon request (n=131). Self-perceived health was used as effect measure; costs encompassed: intervention, healthcare, patient and family, and productivity costs (absenteeism). The cost price year for the study was 2020. Different types of sensitivity analysis were conducted.

resultsAt 12 months of follow-up, the intervention group showed greater effects and higher costs, indicating positive incremental cost-effectiveness ratios (ICERs) of €39.19 and €39.77 per point improvement of self-perceived health, seen from the societal and healthcare perspective. Using the employer perspective, the ICER for the IPS was dominant (preferred) to the control, with (€-3.92) per point improvement of self-perceived health, indicating greater effects and lower costs, related to the net savings for the employer due to reduced sickness absence.

conclusionThe economic evaluation showed that the IPS had an economic benefit over the care as usual, as seen from the employer's perspective. In addition, this approach indicates a way towards a balanced comparison of preventive interventions, which is to prioritize the most relevant preventive actions.

Indexed as

Cost effectivenessEconomic evaluationPreventive interventionRCTSick leave

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.