Evidence map›Paper›PMID 42778612›Full record

ArticleNature2026

Targeting ZMYND8 unleashes IL-2 signalling to override T cell exhaustion.

Yan Wang, Hao Shi, Nicole M Chapman, Anil Kc, Renqiang Sun, Hao Song, Xiaoxi Meng, Xiang Sun, Hongbo Chi

Abstract read
PubMed Publisher
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yan Wang *Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.ORCID http://orcid.org/0000-0003-4779-9967
Hao Shi *Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.ORCID http://orcid.org/0000-0002-2796-629X
Nicole M ChapmanDepartment of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.ORCID http://orcid.org/0000-0003-4710-1776
Anil KcDepartment of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Renqiang SunDepartment of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Hao SongDepartment of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Xiaoxi MengDepartment of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Xiang SunDepartment of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Hongbo ChiDepartment of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA. hongbo.chi@stjude.org.ORCID http://orcid.org/0000-0002-9997-2496

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CD8

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.