Evidence map›Paper›PMID 42778595›Full record

ArticleNature2026

A methanogen hydrolase reveals the structure of archaeal peptidoglycan.

Robert Smith, Nika Pende, Aline Rifflet, Najwa Taib, Jerzy Witwinowski, Camille Martin-Gallausiaux, Charlène Cornilleau, Pierre Simon Garcia, Romain Villa, Thibaut Douché and 13 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Robert Smith *Institut Pasteur, Université Paris Cité, Unit Evolutionary Biology of the Microbial Cell, Paris, France.
Nika Pende *Institut Pasteur, Université Paris Cité, Unit Evolutionary Biology of the Microbial Cell, Paris, France.ORCID http://orcid.org/0000-0001-6986-0090
Aline RiffletInstitut Pasteur, Université Paris Cité, INSERM U1306, Unit Biology and Genetics of the Bacterial Cell Wall, Paris, France.
Najwa TaibInstitut Pasteur, Université Paris Cité, Unit Evolutionary Biology of the Microbial Cell, Paris, France.ORCID http://orcid.org/0000-0002-1422-043X
Jerzy WitwinowskiInstitut Pasteur, Université Paris Cité, Unit Evolutionary Biology of the Microbial Cell, Paris, France.
Camille Martin-GallausiauxInstitut Pasteur, Université Paris Cité, Unit Evolutionary Biology of the Microbial Cell, Paris, France.ORCID http://orcid.org/0000-0002-6193-4304
Charlène CornilleauInstitut Pasteur, Université Paris Cité, Unit Evolutionary Biology of the Microbial Cell, Paris, France.
Pierre Simon GarciaInstitut Pasteur, Université Paris Cité, Unit Evolutionary Biology of the Microbial Cell, Paris, France.ORCID http://orcid.org/0000-0001-7444-899X
Romain VillaInstitut Pasteur, Université Paris Cité, Unit Evolutionary Biology of the Microbial Cell, Paris, France.ORCID http://orcid.org/0009-0001-2427-6779
Thibaut DouchéInstitut Pasteur, Université Paris Cité, CNRS UAR2024, Proteomics Platform, Mass Spectrometry for Biology UtechS, Paris, France.ORCID http://orcid.org/0000-0001-8627-6726
Mariette MatondoInstitut Pasteur, Université Paris Cité, CNRS UAR2024, Proteomics Platform, Mass Spectrometry for Biology UtechS, Paris, France.ORCID http://orcid.org/0000-0003-3958-7710
Manuel MajrouhInstitut Pasteur, Université Paris Cité, Ultrastructural BioImaging Unit, Paris, France.ORCID http://orcid.org/0009-0008-7826-6198
Robert ReicheltInstitute of Microbiology and Archaea Centre, University of Regensburg, Regensburg, Germany.
Dina GrohmannInstitute of Microbiology and Archaea Centre, University of Regensburg, Regensburg, Germany.
Patrick TrippMolecular Biology of Archaea, Faculty of Biology, University of Freiburg, Freiburg, Germany.
Sonja-Verena AlbersMolecular Biology of Archaea, Faculty of Biology, University of Freiburg, Freiburg, Germany.ORCID http://orcid.org/0000-0003-2459-2226
Guillaume BorrelInstitut Pasteur, Université Paris Cité, Unit Evolutionary Biology of the Microbial Cell, Paris, France.ORCID http://orcid.org/0000-0003-4893-8180
Simon K-M R RittmannArchaea Physiology and Biotechnology Group, University of Vienna, Vienna, Austria.ORCID http://orcid.org/0000-0002-9746-3284
Anna Sartori-RuppInstitut Pasteur, Université Paris Cité, Centre de Ressources et Recherches Technologiques (C2RT), Nanoimaging Core Facility, Paris, France.ORCID http://orcid.org/0000-0001-8540-9910
Richard WheelerInstitut Pasteur, Université Paris Cité, INSERM U1306, Unit Biology and Genetics of the Bacterial Cell Wall, Paris, France.ORCID http://orcid.org/0000-0002-9249-2377
J Iñaki GuijarroInstitut Pasteur, Université Paris Cité, CNRS UMR3528, Biological NMR and HDX-MS Technological Platform, Paris, France.ORCID http://orcid.org/0000-0002-3826-5245
Ivo Gomperts BonecaInstitut Pasteur, Université Paris Cité, INSERM U1306, Unit Biology and Genetics of the Bacterial Cell Wall, Paris, France. ivo.gomperts-boneca@pasteur.fr.ORCID http://orcid.org/0000-0001-8122-509X
Simonetta GribaldoInstitut Pasteur, Université Paris Cité, Unit Evolutionary Biology of the Microbial Cell, Paris, France. simonetta.gribaldo@pasteur.fr.ORCID http://orcid.org/0000-0002-7662-021X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peptidoglycan (PG) is a near-universal and essential feature of bacterial cell walls and a major antimicrobial target

Identifiers

PMID42778595

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.