Evidence map›Paper›PMID 42778590›Full record

ArticleNature2026

Lsp2 links early-life diet to adult translation and lifespan in Drosophila.

Hina Kosakamoto, Rina Okada, Clive S Barker, Ayako Isomura-Matoba, Jun Seita, Naoshi Dohmae, Koshi Imami, Fumiaki Obata

Abstract read
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hina KosakamotoLaboratory for Nutritional Biology, RIKEN Center for Biosystems and Dynamics Research, Kobe, Japan.ORCID http://orcid.org/0000-0001-8624-621X
Rina OkadaLaboratory for Nutritional Biology, RIKEN Center for Biosystems and Dynamics Research, Kobe, Japan.
Clive S BarkerLaboratory for Integrative Genomics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
Ayako Isomura-MatobaLaboratory for Nutritional Biology, RIKEN Center for Biosystems and Dynamics Research, Kobe, Japan.ORCID http://orcid.org/0000-0002-8518-9329
Jun SeitaLaboratory for Integrative Genomics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.ORCID http://orcid.org/0000-0002-3008-3615
Naoshi DohmaeBiomolecular Characterization Unit, RIKEN Center for Sustainable Resource Science, Wako, Japan.ORCID http://orcid.org/0000-0002-5242-9410
Koshi ImamiLaboratory for Integrative Genomics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan. koshi.imami@riken.jp.ORCID http://orcid.org/0000-0002-7451-4982
Fumiaki ObataLaboratory for Nutritional Biology, RIKEN Center for Biosystems and Dynamics Research, Kobe, Japan. fumiaki.obata@riken.jp.ORCID http://orcid.org/0000-0002-8641-5818

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nearly a century ago, restricting diet during early-life periods was suggested to extend lifespan in rats and in Daphnia

Indexed as

DietDrosophila melanogasterDrosophila ProteinsLongevityProtein BiosynthesisAmino AcidsAnimalsDietary ProteinsDiet, Protein-RestrictedFemaleLarvaMaleRibosomal ProteinsAmino AcidsDietary ProteinsDrosophila Proteinslarval serum protein, DrosophilaRibosomal Proteins

Identifiers

PMID42778590
PMCPMC13645648

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.