Evidence map›Paper›PMID 42777776›Full record

ArticlePhysics in medicine and biology2026

Physicochemical modeling of electron FLASH to identify the roles of oxygen, aqueous electrons and causal radical recombination effects underlying them.

William S Thomas, Xu Cao, David J Gladstone, Harold M Swartz, Brian W Pogue

Abstract read
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In one paragraph

Article in Physics in medicine and biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

William S ThomasDepartment of Medical Physics, University of Wisconsin School of Medicine and Public Health, Wisconsin, WI 53705, United States of America.ORCID 0009-0005-9829-1794
Xu CaoThayer School of Engineering at Dartmouth, Hanover, NH 03755, United States of America.ORCID 0000-0002-8749-1716
David J GladstoneThayer School of Engineering at Dartmouth, Hanover, NH 03755, United States of America.ORCID 0000-0002-4086-0297
Harold M SwartzThayer School of Engineering at Dartmouth, Hanover, NH 03755, United States of America.
Brian W PogueDepartment of Medical Physics, University of Wisconsin School of Medicine and Public Health, Wisconsin, WI 53705, United States of America.ORCID 0000-0002-9887-670X

Funding

Optimization of MeV FLASH radiotherapy for normal tissue preservationU01CA260446 · NCI · DARTMOUTH COLLEGE · PI David J. Gladstone, Jack Hoopes · 2022 to 2026
$3.1M
Oxygen Dynamics in FLASH RadiotherapyR01CA271330 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Brian William Pogue, Sergei Vinogradov · 2023 to 2026
$2.1M
NCI NIH HHS R01 CA271330NCI NIH HHS U01 CA260446
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ElectronsModels, ChemicalOxygenWaterAnimalsKineticsOxygenWaterFLASHoxygenROSsimulationUHDR

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.