Evidence map›Paper›PMID 42777581›Full record

ArticleJACC. Advances2026

Temporal Trends in Mitral Valve Repair Procedures and Outcomes Among Older U.S. Adults.

Philipp von Stein, David J Cohen, Martin B Leon, Alexandra Popma, Jennifer von Stein, Maria C Alu, Bjorn Redfors, Batla Falah, Juan F Granada, Jeffrey J Popma and 1 more

Abstract read
In one paragraph

Article in JACC. Advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Philipp von SteinCardiovascular Research Foundation, New York, New York, USA; Department of Cardiology, Heart Center, Faculty of Medicine, University of Cologne, Cologne, Germany.
David J CohenCardiovascular Research Foundation, New York, New York, USA; St. Francis Hospital and Heart Center, Roslyn, New York, USA.
Martin B LeonCardiovascular Research Foundation, New York, New York, USA; Columbia-Presbyterian Medical Center, New York, New York, USA.
Alexandra PopmaCardiovascular Research Foundation, New York, New York, USA.
Jennifer von SteinCardiovascular Research Foundation, New York, New York, USA; Department of Cardiology, Heart Center, Faculty of Medicine, University of Cologne, Cologne, Germany.
Maria C AluCardiovascular Research Foundation, New York, New York, USA.
Bjorn RedforsCardiovascular Research Foundation, New York, New York, USA; Weill-Cornell University Medical Center, New York, New York, USA.
Batla FalahCardiovascular Research Foundation, New York, New York, USA.
Juan F GranadaCardiovascular Research Foundation, New York, New York, USA.
Jeffrey J PopmaCardiovascular Research Foundation, New York, New York, USA; Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
Harun KundiCardiovascular Research Foundation, New York, New York, USA. Electronic address: hkundi@crf.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMitral valve (MV) transcatheter edge-to-edge repair (M-TEER) has reshaped the management of mitral regurgitation in high surgical risk patients. As M-TEER adoption expands, understanding concurrent changes in procedural utilization, patient characteristics, and clinical outcomes is important.

objectivesThe objective of the study was to evaluate temporal trends in procedural utilization, comorbidity burden, and mortality among Medicare beneficiaries undergoing MV repair.

methodsMedicare beneficiaries undergoing MV repair between 2017 and 2021 were analyzed. Procedure volumes, Elixhauser Comorbidity Index, and mortality at 30-days, 30-days postdischarge, 1-year, and 2-years were assessed. Temporal mortality trends were analyzed using adjusted Cox models with calendar year as a continuous variable.

resultsAmong 81,215 beneficiaries, 39,097 underwent M-TEER and 42,118 surgical MV repair. M-TEER utilization increased from 15.0 to 27.6 per 100,000 beneficiaries (+84.0%), whereas surgical MV repair decreased from 29.1 to 20.7 per 100,000 (-28.9%), resulting in a 9.5% overall increase in MV repair use. The Elixhauser Comorbidity Index increased overall (+7.8%), remained stable among M-TEER patients (-0.2%), and decreased among surgical MV repair patients (-5.1%). Overall, adjusted mortality decreased at 30-days (adjusted HR [aHR]: 0.92; 95% CI: 0.89-0.94; P < 0.001), postdischarge 30-days (aHR: 0.93; 95% CI: 0.89-0.97; P < 0.001), 1-year (aHR: 0.98; 95% CI: 0.97-1.00; P = 0.013), and 2-years (aHR: 0.98; 95% CI: 0.97-0.99; P < 0.001).

conclusionsBetween 2017 and 2021, M-TEER utilization increased substantially whereas surgical MV repair declined, resulting in increased overall MV repair utilization. Over the same period, adjusted short-term and midterm mortality improved despite a higher overall comorbidity index.

Indexed as

mitral regurgitationmitral valve repairmitral valve transcatheter edge-to-edge repairM-TEERsurgical mitral valve repairutilization trends

Identifiers

PMID42777581
PMCPMC13634761

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