Evidence map›Paper›PMID 42777060›Full record

ArticleScience advances2026

Thalamofrontal synaptic weakening underlies short-term memory deficits from adolescent NMDAR hypofunction.

Jinseon Yu, In Sun Choi, Gyu Hyun Kim, Sangkyu Bahn, Jinmo Kim, Sungwon Bae, Taekwan Lee, Joon Ho Choi, Jun Soo Kwon, Minah Kim and 3 more

Abstract read
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jinseon YuSensory and Motor Systems Research Group, Korea Brain Research Institute (KBRI), Daegu, Republic of Korea.ORCID 0009-0001-7526-898X
In Sun ChoiSensory and Motor Systems Research Group, Korea Brain Research Institute (KBRI), Daegu, Republic of Korea.ORCID 0000-0003-4189-8542
Gyu Hyun KimNeural Circuits Research Group, KBRI, Daegu, Republic of Korea.ORCID 0000-0003-0503-187X
Sangkyu BahnCognitive Science Group, KBRI, Daegu, Republic of Korea.ORCID 0000-0002-1263-7506
Jinmo KimDepartment of Electrical Engineering and Computer Science, DGIST, Daegu, Republic of Korea.ORCID 0000-0001-9766-5874
Sungwon BaeSensory and Motor Systems Research Group, Korea Brain Research Institute (KBRI), Daegu, Republic of Korea.ORCID 0000-0002-9022-8273
Taekwan LeeBrain Research Core Facility, KBRI, Daegu, Republic of Korea.ORCID 0000-0003-2868-5331
Joon Ho ChoiSensory and Motor Systems Research Group, Korea Brain Research Institute (KBRI), Daegu, Republic of Korea.ORCID 0000-0002-2090-8724
Jun Soo KwonDepartment of Psychiatry, Hanyang University Hospital, Seoul, Republic of Korea.ORCID 0000-0002-1060-1462
Minah KimInstitute of Human Behavioral Medicine, Seoul National University (SNU) Medical Research Center, Seoul, Republic of Korea.ORCID 0000-0001-8668-0817
Ji-Woong ChoiDepartment of Electrical Engineering and Computer Science, DGIST, Daegu, Republic of Korea.ORCID 0000-0001-9109-3860
Kea Joo LeeNeural Circuits Research Group, KBRI, Daegu, Republic of Korea.ORCID 0000-0002-1366-4709
Jong-Cheol RahSensory and Motor Systems Research Group, Korea Brain Research Institute (KBRI), Daegu, Republic of Korea.ORCID 0000-0003-3780-0522

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thalamofrontal (TF) dysconnectivity is one of the most consistent circuit-level abnormalities reported in patients with schizophrenia and is linked to deficits in short-term memory (STM). However, the biological mechanisms underlying TF weakening remain unclear. Here, we show that repeated adolescent

Indexed as

Memory DisordersMemory, Short-TermPrefrontal CortexReceptors, N-Methyl-D-AspartateSynapsesThalamusAnimalsKetamineMaleMiceSynaptic TransmissionKetamineReceptors, N-Methyl-D-Aspartate

Identifiers

PMID42777060
PMCPMC13600250

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.