Evidence map›Paper›PMID 42776940›Full record

ArticleNeuroepidemiology2026

Incidence and Survival of Central Nervous System Tumors in Reunion Island: A Population-Based Study.

Mohamed Khettab, Marion Imara, Yves-Marie Diarra, Yosra Bedoui, Auguste Delattre, Johan Encaoua, Sébastien Freppel, Florian Lamblin, Emmanuel Chirpaz, Franck Ah-Pine and 1 more

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Article in Neuroepidemiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Mohamed KhettabDepartment of Oncology, CHU de La Réunion, Saint-Pierre, France, mohamed.khettab@chu-reunion.fr.
Marion ImaraEPI Unit, Université de La Réunion, Saint-Pierre, France.
Yves-Marie DiarraRéunion Cancer Registry, CHU de La Réunion, Saint Pierre, France.
Yosra BedouiEPI Unit, Université de La Réunion, Saint-Pierre, France.
Auguste DelattreDepartment of Oncology, CHU de La Réunion, Saint-Pierre, France.
Johan EncaouaDepartment of Radiotherapy, CHU de La Réunion, Saint Pierre, France.
Sébastien FreppelDepartment of Neurosurgery, CHU de La Réunion, Saint Pierre, France.
Florian LamblinDepartment of Neurology, CHU de La Réunion, Saint Pierre, France.
Emmanuel ChirpazRéunion Cancer Registry, CHU de La Réunion, Saint Pierre, France.
Franck Ah-PineEPI Unit, Université de La Réunion, Saint-Pierre, France.
Luc BauchetInstitut de Génomique Fonctionnelle, Université de Montpellier, CNRS, INSERM, Montpellier, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPrimary central nervous system (CNS) tumors are rare but carry significant morbidity and mortality worldwide. Epidemiological data in diverse populations, such as Reunion Island - a multiethnic French and European outermost region - remain scarce. While robust data are available for mainland France, to our knowledge, no comprehensive description of primary CNS tumors in the population of Reunion Island has yet been reported.

methodsWe analyzed primary CNS tumors diagnosed between 2006 and 2020 using the Reunion Island population-based cancer registry. We estimated age-standardized incidence rates, tumor subtype distributions, and survival outcomes and compared them with international data and those from mainland France.

resultsA total of 1,162 cases of primary CNS tumors were identified between 2006 and 2020. ASRs were 8.9 and 10.7 per 100,000 person-years in men and women, respectively. Meningiomas were the most frequent tumors (52.6%), with a markedly higher incidence in women. Glioblastomas represented 26.1% of cases and were more common in men (sex ratio M/F = 1.5), with an ASR of 3.3/100,000 person-years versus 1.8/100,000 person-years in women, and the median net survival was 11.5 months. Age-standardized net survival was 49.6% (95% confidence interval [95% CI]: 43.6-55.6) at 1 year and 6.5% (95% CI: 2.0-9.9) at 5 years.

conclusionThis first comprehensive population-based study of CNS tumors in Reunion Island reveals incidence and survival patterns comparable to those in mainland France, underscoring the value of cancer registries in diverse settings for informing healthcare planning and research.

Indexed as

Central nervous system tumorsEpidemiologyGlioblastomaPopulation-based cancer registryReunion Island

Identifiers

PMID42776940
PMCPMC13690322

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