Evidence map›Paper›PMID 42776679›Full record

ArticleMethods and protocols2026

Method and Analysis of High-Calcium Induced Differentiation of Human Primary Keratinocytes

Sarmistha Mahanty, Dharna Saini

Abstract read
In one paragraph

Article in Methods and protocols, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sarmistha MahantyAmity Institute of Biotechnology, Amity University Haryana, Gurugram 122413, India.ORCID 0000-0002-1111-8827
Dharna SainiAmity Institute of Biotechnology, Amity University Haryana, Gurugram 122413, India.ORCID 0009-0005-9784-1715

Funding

Anusandhan National Research Foundation (ANRF) ANRF/ECRG/2025/004146/LSIndia Alliance Wellcome Trust-DBT IA/E/17/1/503685Wellcome Trust
6 · The paper itself

Abstract

Epidermal development and regeneration rely on the stepwise differentiation of keratinocytes, the primary constituent cells of the epidermis. In the integrated epidermis, keratinocyte differentiation (KD) occurs in response to the increasing calcium gradient. Reflecting this, high-calcium incubation remains a popular approach for inducing KD

Indexed as

epidermis stratificationhigh-calcium incubationhigh-density differentiationkeratinocyte differentiationkeratinsskin barrier

Identifiers

PMID42776679
PMCPMC13600111

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.