ArticleJournal of eye movement research2026
Saccadic Oscillations After Donepezil Administration in Patients with Dementia: Time Course and Clinical Correlates.
Article in Journal of eye movement research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Donepezil, a cholinesterase inhibitor widely used in dementia, can be associated with saccadic oscillations (SO), but their time course and clinical relevance are unclear. In this prospective observational study, 18 patients with dementia underwent video-oculography at baseline (V0), one month (V1), and three months (V2) after initiation or dose escalation of donepezil. SO were counted over a single 30 s recording during visual fixation and in darkness, expressed as events/30 s. Dizziness was assessed with the Dizziness Handicap Inventory (DHI) and the Vestibular Disorders Activities of Daily Living (VADL) scale. Timepoints were compared using the Wilcoxon signed-rank test, and within-patient associations by repeated-measures correlation (rmcorr). SO with fixation increased from a median of 0.0 (interquartile range 0.0-1.0) events/30 s at V0 to 13.5 (7.2-15.8) at V1 (unadjusted
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