Evidence map›Paper›PMID 42776415›Full record

ArticleNeurochemical research2026

Restoration of Normal Occlusion Suppresses the Risk of Dementia.

Munehisa Maeshiba, Hiroshi Kajiya, Keisuke Migita, Kazuko Goto-T, Takayoshi Seki, Takashi Tsuzuki

Abstract read
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In one paragraph

Article in Neurochemical research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Munehisa Maeshiba *Department of Oral Rehabilitation, Fukuoka Dental College, 2-15-1 Tamura, Sawara-ku, Fukuoka, 814-0175, Japan. maeshiba@fdcnet.ac.jp.ORCID https://orcid.org/0009-0003-5851-7416
Hiroshi Kajiya *Oral Medicine Research Center, Fukuoka Dental College, Fukuoka, Japan.ORCID http://orcid.org/0000-0003-3275-3632
Keisuke MigitaDepartment of Drug Informatics, Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan.
Kazuko Goto-TDepartment of Dental Hygiene, Fukuoka College of Health Sciences, Fukuoka, Japan.
Takayoshi SekiDepartment of Oral Rehabilitation, Fukuoka Dental College, 2-15-1 Tamura, Sawara-ku, Fukuoka, 814-0175, Japan.
Takashi TsuzukiDepartment of Oral Rehabilitation, Fukuoka Dental College, 2-15-1 Tamura, Sawara-ku, Fukuoka, 814-0175, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tooth loss is associated with a progressive decline in cognitive ability. Although occlusal support after tooth loss using dentures may reverse this effect, the underlying mechanisms are unclear, hampering improved evidence-based dentistry for at-risk patients. The current experiments examined the associations of tooth loss and restoration of occlusal support with neuropathology and cognitive decline in a mice model of Alzheimer's disease (AD). A triple-mutant knock-in mouse model of AD (App

Indexed as

Alzheimer DiseaseDementiaDental OcclusionAmyloid beta-PeptidesAmyloid beta-Protein PrecursorAnimalsHippocampusMaleMiceMice, Inbred C57BLMice, Transgenictau ProteinsAmyloid beta-PeptidesAmyloid beta-Protein Precursortau ProteinsAlzheimer’s diseaseAmyloid-βC57BL/6-App<tm1(NL)> AppNL miceC57BL/6-App<tm3(NL−G−F) AppNL−G−F miceInterleukin-1βNormal occlusal supportPhosphorylated Tau

Identifiers

PMID42776415

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.