ArticleJapanese journal of ophthalmology2026
Dry eye outcomes after endonasal dacryocystorhinostomy: tear film changes and risk factors for symptom deterioration.
Article in Japanese journal of ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo evaluate postoperative changes in tear film, ocular surface, and meibomian gland parameters following successful endonasal dacryocystorhinostomy (en-DCR) and predictive factors in postoperative dry-eye symptom deterioration in patients with primary acquired nasolacrimal duct obstruction (PANDO). STUDY
designSingle-center prospective observational study.
methodsThis study included 50 patients with unilateral PANDO who underwent successful en-DCR. Tear film break-up time (TFBUT), Schirmer test, tear meniscus height (TMH), meibomian gland parameters, and dry eye-related symptoms were assessed preoperatively and 3 months postoperatively. Measurements were compared between affected and unaffected eyes, and between pre- and postoperative visits. Patients were categorized into unchanged/improvement or deterioration groups based on postoperative symptom changes. Multivariate logistic regression was performed to identify risk factors for postoperative deterioration.
resultsPostoperatively, the affected eyes demonstrated significant reductions in TFBUT, Schirmer values, and upper and lower TMH, while the fellow eyes remained unchanged. Meibomian gland function significantly improved after surgery. Subjective dry eye symptoms remained unchanged or improved in the majority of the patients. However, 15 patients (30.0%) experienced postoperative symptom deterioration. Patients in the deterioration group had significantly longer preoperative TFBUT and lower DEQS scores. Multivariate analysis showed that lower preoperative upper TMH tended to be associated with an increased risk of postoperative symptom deterioration.
conclusionsRestoration of lacrimal drainage by en-DCR was associated with significant postoperative changes in tear film and ocular surface parameters, together with improvement in meibomian gland function. Lower preoperative upper TMH may be a potential risk factor for postoperative worsening of dry eye symptoms.
Indexed as
Identifiers
42776410What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.