Evidence map›Paper›PMID 42776353›Full record

ReviewStress biology2026

Cross-kingdom RNA in plant-microbe interactions: from molecular interactions to next-generation crop protection.

Borala Liyanage D Deepali, Caiping Huang, Wei Zhang, Hui Wang, Yuan Wang, Kevin D Hyde, K W Thilini Chethana, Jiye Yan

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Stress biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Borala Liyanage D Deepali *Key Laboratory of Environment Friendly Management On Fruit Diseases and Pests in North China, Institute of Plant Protection, Beijing Academy of Agriculture and Forestry Sciences, Beijing, 100097, China.
Caiping Huang *Key Laboratory of Environment Friendly Management On Fruit Diseases and Pests in North China, Institute of Plant Protection, Beijing Academy of Agriculture and Forestry Sciences, Beijing, 100097, China.ORCID http://orcid.org/0000-0002-1359-0412
Wei ZhangKey Laboratory of Environment Friendly Management On Fruit Diseases and Pests in North China, Institute of Plant Protection, Beijing Academy of Agriculture and Forestry Sciences, Beijing, 100097, China.
Hui WangKey Laboratory of Environment Friendly Management On Fruit Diseases and Pests in North China, Institute of Plant Protection, Beijing Academy of Agriculture and Forestry Sciences, Beijing, 100097, China.
Yuan WangKey Laboratory of Environment Friendly Management On Fruit Diseases and Pests in North China, Institute of Plant Protection, Beijing Academy of Agriculture and Forestry Sciences, Beijing, 100097, China.
Kevin D HydeCenter of Excellence in Fungal Research, Mae Fah Luang University, Chiang Rai, 57100, Thailand.
K W Thilini ChethanaSchool of Science, Mae Fah Luang University, Chiang Rai, 57100, Thailand.
Jiye YanKey Laboratory of Environment Friendly Management On Fruit Diseases and Pests in North China, Institute of Plant Protection, Beijing Academy of Agriculture and Forestry Sciences, Beijing, 100097, China. jiyeyan@vip.163.com.ORCID http://orcid.org/0000-0002-4883-4472

Funding

Beijing Academy of Agriculture and Forestry Sciences QNJJ202425National Natural Science Foundation of China 32402301Outstanding Scientist Project of Beijing Academy of Agriculture and Forestry Sciences JKTD2025002
6 · The paper itself

Abstract

Cross-kingdom RNA (CK-RNA) communication is an advanced concept that enhances our understanding of inter-kingdom interactions by uncovering RNA-mediated signaling among plants, fungi, bacteria, and viruses. This review provides a detailed overview of CK-RNA mechanisms, highlighting on plant-microbe interactions. Through RNA interference (RNAi), CK-RNA allows organisms to exchange regulatory signals that influence gene expression, defense responses, metabolism, and adaptive processes across kingdoms. Furthermore, this review highlights agricultural applications of CK-RNA, including Spray-Induced Gene Silencing (SIGS), Host-Induced Gene Silencing (HIGS) and Microbe-Induced Gene Silencing (MIGS) which offer environmentally friendly and sustainable alternatives to conventional chemical management. Overall, the integration of CK-RNAs as target and MIGS as delivery method presents a promising pathway for viable, environmentally friendly crop protection that aligns with modern goals of environmental sustainability and agricultural resilience.

Indexed as

Cross Kingdom RNAHost induced gene silencingMicrobe induced gene silencingRNA PesticidesSpray induced gene silencing

Identifiers

PMID42776353
PMCPMC13601393

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.