ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2026
Nationwide epidemiology of retinitis pigmentosa in Japan, 2011-2020: a population-based cohort study.
Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
purposeRetinitis pigmentosa (RP) is an inherited retinal disorder with limited contemporary national epidemiological data. This study aimed to describe the nationwide epidemiology of RP in Japan using a comprehensive national health insurance claims database.
methodsThis population-based longitudinal cohort study included approximately 126 million individuals covered by Japan's universal health coverage system. Data from the National Database of Health Insurance Claims from 2011 to 2020 were analysed. Patients with RP were identified as those who either had a confirmed RP diagnosis on electroretinography or had a confirmed RP diagnosis and received RP-specific treatment (e.g., helenien or vitamin A). Prevalence and incidence rates were calculated, and age-standardised rates were derived using the World Health Organization standard world population. Regional differences, mortality, and age at cataract surgery were also assessed.
resultsAs of October 1, 2020, 52,964 RP cases were identified, corresponding to a prevalence of 42.0 per 100,000 persons (approximately 1:2,400). The incidence rate was 2.52 per 100,000 person-years. Incidence was higher in southwestern Japan, particularly Kyushu and Shikoku, and lower in northern regions. The mean age at death was 81.7 ± 10.9 years. The mean age at cataract surgery was 68.6 ± 11.6 years.
conclusionThis nationwide population-based study provides updated epidemiological data on RP in Japan, revealing higher prevalence than previously reported, geographic variation, and earlier age at the time of cataract surgery. These findings may inform clinical management, healthcare planning, and future research and clinical trials in inherited retinal diseases.
Indexed as
Identifiers
42776253What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.