Evidence map›Paper›PMID 42776251›Full record

ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2026

Interpreting prediagnostic corticosteroid use in Acanthamoeba keratitis: corticosteroid type and inflammatory phenotype.

Suguru Nakagawa, Hiroko Takano, Machiko Shimmura-Tomita, Toshikatsu Kaburaki

Abstract readLetter
PubMed Publisher
In one paragraph

Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Suguru NakagawaDepartment of Ophthalmology, Saitama Medical Center, Jichi Medical University, 1-847 Amanuma-cho, Omiya-ku, Saitama, Saitama, 330-8503, Japan. snakagawa-tky@umin.ac.jp.ORCID https://orcid.org/0000-0001-9938-4881
Hiroko TakanoDepartment of Ophthalmology, Saitama Medical Center, Jichi Medical University, 1-847 Amanuma-cho, Omiya-ku, Saitama, Saitama, 330-8503, Japan.
Machiko Shimmura-TomitaDepartment of Ophthalmology, Saitama Medical Center, Jichi Medical University, 1-847 Amanuma-cho, Omiya-ku, Saitama, Saitama, 330-8503, Japan.
Toshikatsu KaburakiDepartment of Ophthalmology, Saitama Medical Center, Jichi Medical University, 1-847 Amanuma-cho, Omiya-ku, Saitama, Saitama, 330-8503, Japan.

Funding

Japan Society for the Promotion of Science 24K12750Japan Society for the Promotion of Science 25K12854
6 · The paper itself

Abstract

key messagesWHAT IS KNOWN : Prediagnostic corticosteroid use in Acanthamoeba keratitis has often been associated with delayed diagnosis and poor outcomes, although its independent prognostic significance remains uncertain. WHAT IS NEW: Prediagnostic corticosteroid exposure may warrant characterization beyond a binary variable; corticosteroid agent/type and relative potency remain hypothesis-generating considerations. Keratic precipitates are nonspecific and may represent one component of the inflammatory phenotype; their prognostic significance in Acanthamoeba keratitis remains exploratory.

Indexed as

Acanthamoeba keratitisInflammatory phenotypeKeratic precipitatesPrediagnostic corticosteroid exposureTherapeutic keratoplastyTopical corticosteroid type

Identifiers

PMID42776251

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.