Evidence map›Paper›PMID 42776201›Full record

ReviewDie Anaesthesiologie2026

[Autoimmune encephalitis in intensive care medicine : Differentiation from infectious encephalitis].

Albrecht Günther, Dirk Brämer

Abstract readReviewEnglish Abstract
In one paragraph

Review in Die Anaesthesiologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Albrecht GüntherKlinik für Neurologie, Universitätsklinikum Jena, Am Klinikum 1, 07747, Jena, Deutschland. Albrecht.guenther@med.uni-jena.de.
Dirk BrämerKlinik für Neurologie, Universitätsklinikum Jena, Am Klinikum 1, 07747, Jena, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autoimmune encephalitis (AIE) is a relatively new group within the spectrum of encephalitic diseases. Awareness and the pathophysiological understanding of these conditions are increasing. They are also gaining importance in the field of intensive care medicine as severe cases are frequently accompanied by unconsciousness, epileptic seizures up to treatment-refractory status epilepticus, autonomic dysregulation and the need for mechanical ventilation. A major challenge is the early differentiation between autoimmune and infectious encephalitides as symptoms, cerebrospinal fluid findings and changes in imaging examinations can often appear similar. While infectious encephalitis requires rapid anti-infective therapy, autoimmune forms necessitate early initiation of immunotherapy. Delays in commencing treatment worsen the prognosis. This article addresses the diagnostic criteria, antibody diagnostics, complications in intensive care settings and current immunotherapies.

Indexed as

Critical CareEncephalitisHashimoto DiseaseInfectious EncephalitisAutoantibodiesDiagnosis, DifferentialHumansImmunotherapyAutoantibodiesAntibody diagnosticsAnti-NMDA-receptor encephalitisDifferential diagnosisImmunotherapyStatus epilepticus

Identifiers

PMID42776201
PMCPMC13633355

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.