Evidence map›Paper›PMID 42775896›Full record

ArticleFEMS microbiology letters2026

A comprehensive report on the 1st Swiss-EUCAST antimicrobial susceptibility testing (AST) meeting.

Hendrik Koliwer-Brandl, Stefano Mancini, Barbara Juliane Holzknecht, Rafael Cantón, Laurent Poirel, Helena Seth-Smith, Sören Gatermann, Marlène Amara, Carmen Ardanuy, Oliver Nolte and 1 more

Abstract read
In one paragraph

Article in FEMS microbiology letters, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hendrik Koliwer-BrandlInstitute of Medical Microbiology, University of Zurich, Zurich 8006, Switzerland.ORCID 0000-0003-1613-5615
Stefano ManciniInstitute of Medical Microbiology, University of Zurich, Zurich 8006, Switzerland.
Barbara Juliane HolzknechtDepartment of Clinical Microbiology, Copenhagen University Hospital-Herlev and Gentofte, Herlev 2730, Denmark.
Rafael CantónServicio de Microbiología, Hospital Universitario Ramón y Cajal and Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid 28034, Spain.ORCID 0000-0003-1675-3173
Laurent PoirelMedical and Molecular Microbiology, Faculty of Science and Medicine, University of Fribourg, Fribourg 1700, Switzerland.ORCID 0000-0001-5160-5286
Helena Seth-SmithInstitute of Medical Microbiology, University of Zurich, Zurich 8006, Switzerland.
Sören GatermannDepartment of Medical Microbiology, Ruhr-Universität Bochum, Bochum 44801, Germany.ORCID 0000-0002-8662-218X
Marlène AmaraCNR Bactéries anaérobies et Botulisme, Institut Pasteur, 75724, Paris 75724, France.
Carmen ArdanuyServicio de Microbiología, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Barcelona 08907, Spain.ORCID 0000-0003-0225-607X
Oliver NolteInstitute of Medical Microbiology, University of Zurich, Zurich 8006, Switzerland.
Adrian EgliInstitute of Medical Microbiology, University of Zurich, Zurich 8006, Switzerland.ORCID 0000-0002-3564-8603

Funding

European Society of Clinical Microbiology and Infectious DiseasesSwiss National Science Foundation IZSEZ0_241653/1
6 · The paper itself

Abstract

Antimicrobial susceptibility testing (AST) is being reshaped by increasingly complex resistance mechanisms, revised interpretive frameworks, and rapid phenotypic and genomic technologies. The first Swiss-EUCAST AST Meeting, held in Zurich on 4 May 2026, brought together more than 100 clinical microbiologists, researchers, and infectious diseases specialists to discuss how these developments should be translated into routine diagnostics. The meeting focused on three topics: the limitations of genotype-phenotype prediction, the ongoing need for standardized interpretation within the European Committee on Antimicrobial Susceptibility Testing (EUCAST), and the potential of new technologies to reduce turnaround times. Discussions specifically on Pseudomonas aeruginosa, as well as on pathogens without clinical breakpoints, carbapenemase-producing Enterobacterales, expected phenotypes, epidemiological cutoff values, rapid phenotypic susceptibility tests, and whole-genome sequencing, showed that no single method can eliminate all diagnostic uncertainties. In summary, it was concluded that standardized phenotypic ASTs will continue to serve as a clinical reference in the future, but molecular and genomic methods offer additional advantages in terms of speed, as well as insights into mechanisms of action and epidemiological relations.

Indexed as

Anti-Bacterial Agentsbeta-LactamasesDrug Resistance, BacterialHumansMicrobial Sensitivity TestsPhenotypePseudomonas aeruginosaSwitzerlandAnti-Bacterial Agentsbeta-Lactamasesantimicrobial resistanceantimicrobial susceptibility testingcarbapenemase-producing Enterobacteralesclinical breakpointsepidemiological cutoff valuesEUCASTmedical microbiologyrapid phenotypic ASTwhole-genome sequencing

Identifiers

PMID42775896
PMCPMC13640028

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.