ArticleApplied and environmental microbiology2026
Sulfur source-driven global remodeling of gene expression in the fuel-biodesulfurizing
Article in Applied and environmental microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Recent proteomics and metabolomics studies have confirmed the significance of understanding the fuel biodesulfurization phenotype at a global scale beyond the desulfurization 4S pathway. To reveal the transcriptomic adaptations in the model strain IMPORTANCE: Commercial application of fuel biodesulfurization requires exceptionally robust and catalytically active desulfurizing microbes that can tolerate and sustain activity under the harsh operational conditions in oil refineries. It is generally accepted that naturally occurring bacteria may not meet these industrial requirements. Therefore, synthetic biology and metabolic engineering hold promise. However, a thorough understanding of the physiology, metabolism, and stress response of fuel-desulfurizing bacteria, which is currently lacking, is key toward further developments in this field. Considering these knowledge gaps, our findings provide mechanistic insights into the transcriptional responses of the reference biodesulfurizing strain
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