ArticleJournal of applied clinical medical physics2026
Feasibility of lattice radiation therapy using a noncoplanar vertex arrangement and dynamic conformal arcs.
Article in Journal of applied clinical medical physics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundCurrent Lattice radiation therapy (LRT) mainly uses inverse IMRT/VMAT optimization, which is time-consuming and complex; however the high modulation complexity compromises dosimetric accuracy and blurs the peak‑to‑valley dose ratio. PURPOSE: This study presents a simple noncoplanar vertex arrangement for dynamic conformal arc (DCA)‑based LRT and evaluates its feasibility.
methodsDifferent noncoplanar vertex geometries were generated in a water phantom, and DCA‑based LRT plans were designed using Eclipse v15.6 (Varian). The LRT target volume (LTV) was the union of all vertices. Single‑fraction 20‑Gy plans were generated with three coplanar 6‑MV FFF beams and calculated with AcurosXB calculation. Optimal vertex geometry was selected based on high‑dose proportion (measured with the volume ratio of prescribed dose structure to GTV [V
resultsIn the phantom, six noncoplanar vertex configurations and one coplanar vertex configuration were generated, and corresponding DCA plans were designed for each. All plans achieved a high‑dose volume proportion exceeding 1% and EUD
conclusionsDCA‑based LRT with noncoplanar vertices is feasible on linacs, simplifying planning and enabling accurate delivery. It offers a valuable alternative method for patients with couch rotation limit. Optimal vertex arrangement with 1‑cm diameter and 3.5-4 cm center to center distance obtained in water phantom. Two patient cases met LRT criteria, with a total planning time of approximately one hour per patient, supporting clinical applicability in complex anatomies.
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