Evidence map›Paper›PMID 42775385›Full record

ArticleAdvanced biomedical research2026

The Role of Different Domains of Perceived Stress in the Development of Cardiovascular Events: A Cohort Study.

Hamidreza Roohafza, Farshad Rostampour, Ali Safaei, Fatemeh Nouri, Mohammad Talaei, Mansoureh Boshtam, Nizal Sarrafzadegan, Masoumeh Sadeghi

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Article in Advanced biomedical research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Hamidreza RoohafzaDepartment of Psychocardiology, Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Farshad RostampourIsfahan Cohort Study Department, Heart Failure Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Ali SafaeiIsfahan Cohort Study Department, Heart Failure Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Fatemeh NouriBiostatistics Department, Hypertension Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Mohammad TalaeiInstitute of Population Health Sciences, Barts and the London School of Medicine, Queen Mary University of London, London, UK.
Mansoureh BoshtamIsfahan Cohort Study Department, Interventional Cardiology Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Nizal SarrafzadeganIsfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Masoumeh SadeghiCardiac Rehabilitation Department, Cardiac Rehabilitation Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Long-term distress plays a crucial role in the development and prognosis of cardiovascular events (CVEs). The current study aims to evaluate the role of distress and its domains in the pathogenesis of CVE. Materials and Methods: This study is part of the Isfahan Cohort Study conducted on 3283 healthy individuals in 2007-2015 to assess the distress level, domains of perceived stressors, and their correlation with CVE development. The demographic and lifestyle characteristics of the studied population were recorded. General Health Questionnaire-12 (GHQ-12) and the Stressful Life Event questionnaire (SLE) were applied to investigate the stress level and its domains, respectively. Kaplan-Meier plots were depicted to show the correlation of CVE incidence with both stress statuses at study entry and the perceived stress level within the 8-year follow-up. Results: The logistic regression assessments showed that the stress score was an independent predictor for CVEs incidence in both crude model ( Conclusions: The current study represented an independent role for long-term distress in the development of CVEs. Besides, home life, financial problems, personal conflicts, loss and separation, and health concerns were the major long-term perceived stressors responsible for CVE development.

Indexed as

Cardiovascular diseasecohort studiespsychological stress

Identifiers

PMID42775385
PMCPMC13597044

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