ArticleInternational journal of developmental disabilities2026
Connection between attention, executive function, episodic memory, and adaptive functioning in young adults with Down syndrome.
Kayla Kristensen, Kumari Anshu, Emily K Schworer, Audra Sterling, Benjamin Handen, Ruth Y Litovsky, Sigan L Hartley
Abstract read
In one paragraphArticle in International journal of developmental disabilities, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
7 authors.
Kayla KristensenWaisman Center, University of Wisconsin-Madison, Madison, WI, USA.
Kumari AnshuWaisman Center, University of Wisconsin-Madison, Madison, WI, USA.
Emily K SchworerWaisman Center, University of Wisconsin-Madison, Madison, WI, USA.
Audra SterlingWaisman Center, University of Wisconsin-Madison, Madison, WI, USA.
Benjamin HandenUniversity of Pittsburgh School of Medicine - Pittsburgh, Pittsburgh, PA, USA.
Ruth Y LitovskyWaisman Center, University of Wisconsin-Madison, Madison, WI, USA.
Sigan L HartleyWaisman Center, University of Wisconsin-Madison, Madison, WI, USA.
Funding
University of Pittsburgh Clinical and Translational Science InstituteUL1TR001857 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2016 to 2025
$129.3MNational Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD)U24AG021886 · NIA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI TATIANA M. FOROUD · 2002 to 2026
$119.8MProject 3: Biomarkers for DS Clinical TrialsU19AG068054 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LEE, JOSEPH HYUNGWOO · 2020 to 2025
$103.7MClinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0MWU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8MUniversity of Wisconsin Institute for Clinical and Translational ResearchUL1TR002373 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI ELIZABETH S BURNSIDE, Allan R. Brasier · 2017 to 2026
$75.9MWASHINGTON UNIVERSITY ALZHEIMERS DISEASE RESEARCH CENTERP50AG005681 · NIA · WASHINGTON UNIVERSITY · PI MORRIS, JOHN · 1985 to 2019
$52.1MSatellite Diagnostic and Treatment Clinic CoreP50AG008702 · NIA · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI DE JAGER, PHILIP L · 1989 to 2019
$46.3MTREATMENT OF DEPRESSION IN ALZHEIMER'S DISEASEP50AG005133 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SWEET, ROBERT A · 1985 to 2019
$43.0MResearch Education ComponentP30AG062421 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI Christine S Ritchie · 2019 to 2026
$36.5MUniversity of California Health Participation in the National COVID Cohort Collaborative (N3C)UL1TR001414 · NCATS · UNIVERSITY OF CALIFORNIA-IRVINE · PI COOPER, DAN M, VILAIN, ERIC J. · 2015 to 2023
$35.1MWisconsin Alzheimer's Disease Research CenterP30AG062715 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI Sanjay Asthana · 2019 to 2026
$34.5MNCATS NIH HHS UL1 TR001414NCATS NIH HHS UL1 TR001857NCATS NIH HHS UL1 TR001873NCATS NIH HHS UL1 TR002345NCATS NIH HHS UL1 TR002373NIA NIH HHS P30 AG062421NIA NIH HHS P30 AG062715NIA NIH HHS P30 AG066519NIA NIH HHS P50 AG005133NIA NIH HHS P50 AG005681NIA NIH HHS P50 AG008702NIA NIH HHS U01 AG051406NIA NIH HHS U01 AG051412NIA NIH HHS U19 AG068054NIA NIH HHS U24 AG021886NICHD NIH HHS P50 HD105353NICHD NIH HHS U54 HD087011NICHD NIH HHS U54 HD090256NIDCD NIH HHS R01 DC003083
6 · The paper itselfAbstract
Objectives: This study examined associations between attention, working memory, inhibition, episodic memory, and adaptive functioning in young adults with Down syndrome (DS). Methods: Forty-seven adults with DS (19-30 years) completed measures of attention, working memory, inhibition, and episodic memory within two studies. Study partners completed the Vineland-3, an informant-report of adaptive functioning. Hierarchical regressions were used to examine associations between attention, working memory, inhibition, episodic memory, and Vineland-3 scores. Results: Participants with DS with an IQ in the mildly and moderately below average range had comparable levels of daily living and socialization skills but differed in communication. All adaptive functioning scores were lower for those with an IQ in the severely below average range. Working memory and episodic memory were positively associated with all Vineland-3 scores except socialization. Inhibition was positively associated with communication and overall adaptive skills. Attention was positively associated with overall adaptive skills. Conclusions: Attention, working memory, inhibition, and episodic memory are associated with the adaptive functioning of adults with DS. Important connections exist between memory and communication and daily living skills, as well as inhibition and communication skills. Future research should explore environmental adaptations for supports in these areas (e.g. assistive technology).
Indexed as
Adaptive functionattentioncognitionDown syndromeeveryday living skillsexecutive functioninhibitionmemory
Identifiers
PMID42775375
PMCPMC13597151
What OpenQuestion holds
Textmetadata
Read underepoch 390