Evidence map›Paper›PMID 42775366›Full record

ReviewAdvanced biomedical research2026

The Pivotal Role of miR-770 in Solid Tumors Carcinogenesis.

Mohsen Davari, Pooran Ghiasizadeh, Mozhgan Mondeali, Mohammadreza Rajabi, Forough Hatami, Sara Zareian

Abstract readReview
In one paragraph

Review in Advanced biomedical research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mohsen DavariDepartment of Medical Biochemistry, Faculty of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Pooran GhiasizadehHygirne Center of Arak, Arak University of Medical Sciences, Arak, Iran.
Mozhgan MondealiDepartment of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Mohammadreza RajabiDepartment of Pathology, Transplant Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Forough HatamiDepartment of Biology, Islamic Azad University of Thran North Branch, Tehran, Iran.
Sara ZareianDepartment of Biology, Faculty of Advanced Sciences and Technology, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs (miRNAs) are known as potential biomarkers for cancer detection and therapeutic management owing to their epigenetic significance in gene expression and other cellular functions. In this review, evidence has been collected to reach the clinical effect and molecular mechanism of miR-770 in various cancers. MiR-770 dysregulation in different malignancies like breast cancer, colorectal cancer, gastric cancer, glioma, liver cancer, lung cancer, oral cancer, prostate cancer, and ovarian cancer has shown a significant decrease or increase in its expression, which indicates it acts as a tumor suppressor or oncogene. MiR-770 participates in cell growth, migration, and invasion via the cellular pathway, WNT (wingless-type MMTV integration site family)/β-catenin signaling pathways, Toll-like receptor signaling pathway, mitogen-activated protein kinases (MAPK) signaling pathway, phosphatidylinositol 3kinase (PI3K)-protein kinase B (AKT) signaling pathway, Notch signaling pathway, erythroblastic leukemia viral oncogene homolog (ErbB) signaling pathway, transforming growth factor-beta (TGF-beta) signaling pathway, Insulin signaling pathway, ubiquitin-dependent proteolysis, Neurotrophin signaling pathway, vascular endothelial growth factor (VEGF) signaling pathway, and T cell and B cell receptor signaling pathway. In the present review, MiR-770 has been introduced as a potential marker in the prognosis of various cancers as well as in the early identification of tumor formation, progression, and metastasis.

Indexed as

BiomarkercancermicroRNAmicroRNA-770miR-770

Identifiers

PMID42775366
PMCPMC13597046

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.