ArticleAnnals of surgery open : perspectives of surgical history, education, and clinical approaches2026
Rapid Pre-Implementation Evaluation for Multi-Specialty Surgical Trials: Informing Context-Specific Adaptations.
Article in Annals of surgery open : perspectives of surgical history, education, and clinical approaches, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Objective: To demonstrate the application of the Consolidated Framework for Implementation Research (CFIR)-guided rapid qualitative methods for pre-implementation evaluation and adaptation of multi-specialty surgical trials. Background: CFIR-guided rapid qualitative methods have proven effective for pre-implementation evaluation in primary care, psychiatry, and critical care. However, their application to surgical contexts-where workflow complexity, specialty-specific practices, and time constraints present unique implementation challenges-remains unexplored. Methods: We conducted CFIR-guided formative evaluation during the pre-implementation phase of a multisite hybrid type I trial that implemented multi-disciplinary frailty optimization across 21 surgical specialty clusters at 3 Veterans Affairs Medical Centers. We employed a multi-method approach including semistructured interviews with 30 stakeholders with surgical leaders, 6 focus groups with 24 PAUSE Board members, and multi-day on-site observations at 3 intervention sites (November 2021-June 2022). Data were analyzed using CFIR-informed rapid content analysis and triangulated to ensure rigor and actionability. Results: Rapid analysis identified implementation barriers and facilitators across CFIR domains, distinguishing between core intervention functions (frailty screening and multidisciplinary optimization) and adaptable elements (screening workflows, personnel roles, communication channels). This approach enabled site- and specialty-specific pre-implementation adaptations across all 21 clusters at 3 sites while aiming to preserve intervention fidelity. Conclusions: This work provides a methodological roadmap for applying CFIR-guided rapid qualitative methods in multi-specialty surgical trials, demonstrating how systematic pre-implementation evaluation can balance fidelity with context-specific adaptation. Our approach offers practical guidance for researchers implementing complex interventions across diverse surgical specialties.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.