ArticleOpen forum infectious diseases2026
Diagnosis and Management of Patients With Suspected Left-Sided Prosthetic Valve Endocarditis According to Cardiac FDG-PET CT Results.
Article in Open forum infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Despite advances in echocardiography, the definitive diagnosis of prosthetic valve endocarditis (PVE) remains difficult. Method: Between 2016 and 2022, 140 patients underwent PET to evaluate suspected left-sided PVE, resulting in 93 patients with positive PET (+PET) and 47 patients with negative PET. Patients were classified as definite, possible, or rejected PVE according to the 2023 Duke-International Society for Cardiovascular Infectious Diseases guidelines, initially excluding and then including PET results. We evaluated the association between PET results and clinical outcomes such as duration of antibiotics, performance of cardiac surgery within 3 months, and long-term mortality. A qualitative analysis of medical decision-making was performed. Results: Demographics were similar between groups. patients with +PET had higher C-reactive protein levels (9.8 vs 3.1 mg/L, Conclusions: Positron emission tomography results, when incorporated into multidisciplinary discussion, aided in a more definitive diagnosis of PVE and influenced management in the majority of patients.
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