Evidence map›Paper›PMID 42775102›Full record

ArticleBioactive materials2027

Zinc silicate microspheres-mediated bacterial metabolic interference and microenvironment remodeling for chronic wound repair.

Fanyan Deng, Zizhuo Liu, Yiran Shao, Xiude Chen, Kexin Zhang, Yanping Feng, Jinyu Zeng, Dong Han, Shunxiang Xu, Congqin Ning

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioactive materials, 2027. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Fanyan DengThe Education Ministry Key Lab of Resource Chemistry and Shanghai Frontiers Science Center of Biomimetic Catalysis and Shanghai Engineering Research Center of Green Energy Chemical Engineering, Shanghai Normal University, Shanghai, PR China.
Zizhuo LiuThe Education Ministry Key Lab of Resource Chemistry and Shanghai Frontiers Science Center of Biomimetic Catalysis and Shanghai Engineering Research Center of Green Energy Chemical Engineering, Shanghai Normal University, Shanghai, PR China.
Yiran ShaoSHNU-YAPENG Joint Lab of Tissue Repair Materials, Shanghai Yapeng Biological Technology Co., Ltd, Shanghai, PR China.
Xiude ChenThe Education Ministry Key Lab of Resource Chemistry and Shanghai Frontiers Science Center of Biomimetic Catalysis and Shanghai Engineering Research Center of Green Energy Chemical Engineering, Shanghai Normal University, Shanghai, PR China.
Kexin ZhangThe Education Ministry Key Lab of Resource Chemistry and Shanghai Frontiers Science Center of Biomimetic Catalysis and Shanghai Engineering Research Center of Green Energy Chemical Engineering, Shanghai Normal University, Shanghai, PR China.
Yanping FengThe Education Ministry Key Lab of Resource Chemistry and Shanghai Frontiers Science Center of Biomimetic Catalysis and Shanghai Engineering Research Center of Green Energy Chemical Engineering, Shanghai Normal University, Shanghai, PR China.
Jinyu ZengSHNU-YAPENG Joint Lab of Tissue Repair Materials, Shanghai Yapeng Biological Technology Co., Ltd, Shanghai, PR China.
Dong HanDepartment of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.
Shunxiang XuDepartment of Orthopaedics and Traumatology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, PR China.
Congqin NingThe Education Ministry Key Lab of Resource Chemistry and Shanghai Frontiers Science Center of Biomimetic Catalysis and Shanghai Engineering Research Center of Green Energy Chemical Engineering, Shanghai Normal University, Shanghai, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic wounds have presented a significant clinical challenge due to persistent infection, uncontrolled inflammation, and impaired tissue regeneration. Existing therapeutic platforms have failed to integrate these critical aspects into a single, cohesive strategy. To address this, a novel multifaceted agent, zinc silicate flower-like microsphere (ZnSi FMPs), was designed with controlled hierarchical architecture to achieve chronic wound repair by mediating bacterial metabolic interference and microenvironment remodeling. The unique nanosheet structure with sustained Zn

Indexed as

AntibacterialChronic woundMetabolic interferenceMicroenvironment remodelzinc silicate microspheres

Identifiers

PMID42775102
PMCPMC13595150

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.